Meaning of repeated tumor biopsy during neoadjuvant chemotherapy (NCT) in patients with ER-positive Her-2/neu negative II-III stage breast cancerdoi:10.1016/j.ejso.2024.108985C. ValeriyM. MilanA. MykolaL. NovokhatskaEuropean Journal of Surgical Oncology...
The HER-2/neu dominant gene is localised in normal human cells as a singular copy on the long arm (q21) of chromosome 17. This gene, first identified in a chemically induced rat neuroblastoma (Schechter et al, 1984), codes for a 185-kDa receptor-type tyrosine protein kinases (p185 neu...
HER一2基因或HER-2/neu基 因又称C-erbB-2基因,位于染色体17q12—21.32,为表皮生长因子受体(EGFR) 家族成员之一,编码1255个具有跨膜酪氨酸激酶活性的生长因子受体,分子量 约185kD,因此又被称为p185。HER一2基因与配体相互作用,通过细胞间信号 传导,调节细胞生长、分化和增殖13J。HER一2基因扩增将导致转录上调...
5.Proto-oncogene HER-2 in Breast Cancer Research原癌基因HER-2在乳腺癌中的研究进展 6.The Expression and Its Clinical Meaning of HER-2/neu Gene in Human Gastric Carcinoma;HER-2/neu基因在胃癌的表达及其临床意义 7.A Study of Breast Cancer ER, PR and HER-2 Oncogene: Expression and Significance...
The Economist: When less is more.“As an aircraft enthusiast since boyhood, your correspondent has long had a special place in his pantheon of heroes for the poet-aviator Antoine de Saint Exupéry, who pondered the meaning of flight as he ferried mail through the North African night in the...
HER3 is often correlated with poorly differentiated biliary tumors [81] and appears to be a poor prognostic factor in EHCCs [76], whereas the prognostic meaning of HER2 has not been completely clarified [79, 87]. Interestingly, the combination of pertuzumab and trastuzumab has been reported to...
was commonly rc a d by readers in a neusp aper in 1978【小题4】 What do the sayings "get your act t ogether" an d "cut to the chase" hare in comm on? A. T heir use. B . T heir meaning. C . T heir origin. D . T heir popularity. ...
1.Human anti-idiotypic antibody Fab or scFv fragment, characterized by the ability to mimic Her-2/neu tumor associated antigen. 2.The fragment of claim 1, that comprises a sequence SEQ ID No: 3 in the CDR3 region of the VH domain and a sequence SEQ ID No: 4 in the CDR3 region ...
et al., Existent T-cell and antibody immunity to HER-2/neu protein in patients with breast cancer. Cancer Res, 1994. 54(1): p. 16-20. Disis, M.L. et al., Immunization of oncogenic HER-s/neu protein with peptide based vaccines. Proceedings of the Annual Meeting of the American ...
Worthington, Urbino Conant, Diamond and Tractatus 6.54 Wolfgang Kienzler, Jena Wittgenstein über „Gedankenexperimente". Gedankenexperimente in der neueren analyti- schen Philosophie und bei Wittgenstein Katalin Neumer, Budapest „Die Gemeinsame menschliche Handlungsweise" in Wittgensteins Nachlass ...