Backgroudandaims:Hepcidinisasmallmolecularpeptidcwhichsecretedbytheliver.Atpresent,itisalreadythoughttobethecentralregulatorofironabsorptionandironbalanceintheorganism.TIliSresearchisforthepurposeofunderstandingtheexpressionlevelofthehepeidingeneanditseffectsonironmetabolisminpatientswithlivercirrhosis....
Gene expression【目的】克隆锦鲤Hepcidin全长c DNA序列(k-hepc),并获得此基因在鱼体内的表达模式。【方法】利用RT-PCR和RACE PCR的方法,从锦鲤肝脏中克隆锦鲤Hepcidin的全长c DNA,进行序列测定和分析;锦鲤经肌肉注射维氏气单胞菌0、4、8、12、24和48 h后,分别取其肝、脾、肾、肠、脑、心、肌肉和鳃组织,...
3.A pair of primers was designed and synthesized according to the bovine Hepcidin gene sequence in Genbank (Accession Number:XM-589792.论文以我国高原牦牛为研究对象,根据GenBank中收录的普通牛Hepcidin基因序列(登录号为XM-589792。 英文短句/例句 1.Clone of the Hepcidin Gene in Yak and Its Prokaryoti...
学校编码:10384分类号学号:B200327007UDC博士学位论文养殖真鲷、黑鲷抗菌肽hepcidin的基因克隆、表达特性及其抗菌活性研究Cloning,ExpressionandAntimicrobialActivityAnalysisofHepcidinGeneVariantsinTwoCulturedFish,PagrusmajorandSpagrusmacrocephalus杨明指导教师姓名:***授王克坚教授专业名称:海洋生物学论文提交日期:2006年6月论文...
2.The direct proof thathepcidincan modulate iron balance of the body was resulted from the observation of the mice whose hepcidin gene were knocked out and overexpressed. 后来通过基因敲除和转基因小鼠的研究进一步得到其调控机体铁平衡的直接证据。 3.Hepcidin , a 25 - amino acid peptide hormone ,...
y[J].Blood,2006,107(1):328-333. [4] NicolasG,BennounM,DevauxL,eta1.Lackofhepcidingeneex— 肿瘤患者贫血患病率 (不包括化疗所致贫血)高 pressionandseveretissueironoverloadupstreanlstimulatoryfactor 达 30%～90% 。支持 hepcidin在 ACD起重要作 2(USF2)knockoutmice[j].ProcNatlAcadSciUSA,200l,98...
铁调素 (hepcidin)及其表达调节 李再山 摘要:铁调素 (hepcidin)是由肝脏分泌的一种多肽,它在调节机体铁平衡中有 重要作用。本文就hepcidin 的生物学特性、功能、及影响hepcidin 的表达调控做 一综述。 关键词:铁调素,膜铁转运蛋白,骨形成蛋白,表达调控 Abstract:Hepcidin, a peptide hormone secreted by the liver, ...
survival, Western Blot method, we try to figure out the effect of the AAV vector-medicated Hepcidin protein overexpression in the reduction of iron overload and the amelioration of the anemia symptoms, and explore its mechanisms.This study may provide more experiment data for the gene therapy of...
温州医学院硕士学位论文论文题目:脓毒症白细胞Hepcidin基因表达水平与铁代谢、。炎症反应的相关性研究‘答辩委员会主席:王塑坦数援答辩委员会成员:一直红敛援全跬威塾援邕匹幽丛区目录中文摘要………3英文摘要………5缩略词表………7前言………8鄹青……...……….………..材料与方法………11结果………....
塾皇巳￡i亟i望i丝里i￡丝垒坠堕i丝巫塑By【MingdaoMU】ADissertationSubmittedtoUniversi蚵ofChineseAcademyofSciencesInpartialfumUmentOftherequirementF0rthedegreeOfMasterof【Bio—Engineering】ShanghaiInstitutesf;I口rBiologicalSciences,CASMay,2014摘要筛选调控铁调素(Hepcidin)表达的活性物质1、黑豆皮提取物抑制...