Nonreactive (negative). This means you're not currently infected with hep C. If you think you've been exposed within the last 6 months, you will need to be tested again to make sure because it can take a while for your antibody levels to rise high enough to be detected on a test. ...
Antibody reactive to a hepatitis C virus (HCV)-derived peptide capable of including HLA-A2 restricted cytotoxic T lymphocytes is detect- able in the majority of HCV-infected individuals without HLA-A2 restriction. Microbiol Immunol 2004;48:507-517....
Hepatitis C virus(HCV), discovered in 1989, was the long sought-after and highly elusive causative agent of post-transfusion non-A, non-B hepatitis. This hugely important discovery allowed rapid development of serological screening assays forHCVinfection and their adoption for blood donor screening....
About 50% of intravenous drug abusers (IVDA), 10% of transfusion recipients and an overall average of 7.9% of male homosexuals were reactive for antibody to HCV. Individuals with jaundice and negative hepatitis B virus (HBV) serology were not reactive for antibody to HCV compared with 26.7% ...
Summary. Stored serum samples from 24 blood donors confirmed positive for anti-HIV-1 were tested for antibody to hepatitis C virus (HCV). Those repeatedly reactive using the anti-HCV ELISA screening test were retested by the HCV recombinant immunoblot (RIBA). Risk-factors for the contraction of...
Hepatitis C virus (HCV)3 is a member of the Flaviviridae family of enveloped positive strand RNA viruses and displays two envelope glycoproteins, E1 (polyprotein residues 191–383) and E2 (E2; residues 384–746), on the virus surface. These type I transmembrane proteins contain heavily glycosyl...
et al. Occurrence of antibodies reactive with more than one variant of the putative envelope glycoprotein (gp70) hypervariable region 1 in viremic hepatitis C virus-infected patients. J Virol 69, 4407–4412 (1995). 27. Mondelli, M. U. et al. Antibody responses to hepatitis C virus ...
it gives many false-positive reactions. In populations with a low pretest probability of carrying hepatitis C, more than 40% of repeatedly reactive specimens are false positives. The antibody that is detected is nonneutralizing; that is, its presence does not confer immunity. If antibody is de...
Antibody to hepatitis C virus was detected in 87% of patients with transfusion-related chronic non-A, non-B hepatitis; 17.6% of patients with nonmalignant, chronic hepatitis B virus infection; 37.3% of patients with hepatocellular carcinoma; 14.3% of patients with alcoholic liver diseases; 22.2%...
Aspects of the present invention relate to the discovery of a novel hepatitis C virus (HCV) isolate. Embodiments include HCV peptides, nucleic acids encoding said HCV peptides, anti