These nine individuals can be divided into two categories: (1) those who yielded a single PCR-positive sample (n 5) and (2) those who yielded an unspecified number of positive samples during the review period (n 4). It is a concern that the authors excluded the first group of PCR-...
Travel-associated acquisition of hepatitis C virus infection in patients receiving haemodialysis METHODS: To characterize the prevalence of antibody-negative/RNA-positive HCV infection, patients attending seven haemodialysis units underwent anti-HCV testing ... A Ghafur,M Raza,W Labbett,... - 《Nephrol...
transcription of the genomic RNA into a full-length negative-polarity copy, which in turn acts as thetemplatefor the production of multiple positive-stranded RNA copies. These can be used for further rounds of transcription, or used for the production of furtherviral proteins. Factors that ...
L. et al. Detection of HIV-1 and HCV infections among antibody-negative blood donors by nucleic acid-amplification testing. N. Engl. J. Med. 351, 760–768 (2004). Article CAS PubMed Google Scholar Pawlotsky, J.-M. et al. EASL recommendations on treatment of hepatitis C: final ...
A systematic virological follow-up of 114 haemodialysis patients treated in the same unit showed that 37, including 17 PCR positive patients, were seropositive for hepatitis C virus (HCV). Type 1b HCV was detected in 10 patients and was much more frequent in this population than in the whole...
There were no cases in which antibodies were detected and polymerase chain reaction (PCR) was negative. Two of the three had mildly elevated liver enzymes and all three had mild inflammatory activity and low fibrosis scores on liver biopsy.Conclusions: The look-back process, even in a single ...
Infection with hepatitis C virus (HCV) is usually diagnosed by the presence of antibodies against fusion proteins or peptides derived from different regions of the HCV genome. However, a subgroup of patients with HCV viraemia are seronegative for antibody against hepatitis C virus (anti-HCV) by...
Anti-HBV prophylaxis reduced de novo infection rates in both anti-HBc/anti-HBs positive (3%) and HBV naive recipients (12%). De novo infection rates were 19%, 2.6% and 2.8% in HBsAg-negative recipients under hepatitis B immunoglobulin, lamivudine and their combination, respectively. Conclusions...
Early incident cases enrolled into a sub-cohort HITS-incident (HITS-i) when new onset viremia, but antibody negative status was recorded. These subjects were then sampled frequently for 12 weeks before antiviral treatment was offered and sometimes taken up after 24 weeks, thereby allowing ...
False negative FP: False positive HCV Ab: HCV antibody HCV: Hepatitis C Virus NAT: Nucleic acid testing NPV: Negative predictive value POC: Point-of-care PPV: Positive predictive value, RCT: Randomised control trial RDTs: Rapid diagnostic tests ...