Step 1: Hepatitis B Surface Antigen (HBsAg) Positive: Go to Step 2 Negative: May still representHepatitis Binactive carrier state Step 2: Differentiate Chronic Infection vsImmunity Hepatitis B Core Antibody Hepatitis B Surface Antibody (immune) ...
2 DOSAGE AND ADMINISTRATION 2.1 Testing Prior to the Initiation of Therapy Test all patients for evidence of current or prior HBV infection by measuring hepatitis B surface antigen (HBsAg) and hepatitis B core antibody (anti-HBc) before initiating HCV treatment with SOVALDI [see Warnings and ...
Infections with the Hepatitis B (HBV) and D (HDV) viruses are the main cause of hepatocellular carcinoma (HCC) and liver cirrhosis as consequences of chronic hepatitis. Although vaccination is possible, more than 250 million people worldwide suffer from chronic hepatitis based on HBV/HDV infection...
(B) Immunoblotting using the anti-HCV core antibody was performed according to the same experimental design described in Fig. 3A. (C) E27, scramble control peptide (1 μ M), or DMSO (0.5%) was added to Huh7.5.1 cells 2 or 4 h prior to (− 2 h and − 4 h)...
Coexistence of hepatitis b virus quasispecies enhances viral replication and the ability to induce host antibody and cellular immune responses. J. Virol. 2014, 88, 8656–8666. [CrossRef] [PubMed] 3. Huang, L.R.; Wu, H.L.; Chen, P.J.; Chen, D.S. An immunocompetent mouse model for...
Moreover, HBV infection requires expression of the human-hepatocyte-specific HBV cell surface receptor. Therefore, the ability to detect HBV replication and Hepatitis B core Antigen (HBcAg) expression in our microfluidic platform confirmed that hepatocyte differentiation and functions were retained through...
Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody. Nat. Biotechnol. 2015, 33, 549–554. [CrossRef] [PubMed] 25. Sainz, B., Jr.; Barretto, N.; Martin, D.N.; Hiraga, N.; Imamura, M.; Hussain, S.; Marsh, K.A.;...