Patients in the group with significant hepatic fibrosis were older (p < 0.001), had lower platelet count values (p = 0.027), serum albumin (p = 0.019), HDL-c (p = 0.013) and Matsuda index (p = 0.044); and high values of LDL-c (p = 0.049), AST (p = 0.001), alanine ...
www.519liver.com 2. It would be beneficialtodisclosing a possiblemechanismofschistosomalhepaticfibrosisand therapy of thisdisease. 为进一步揭示血吸虫病肝纤维化的机制和寻找更有效的防治途径打基础。 www.fabiao.net 3. Atpresent, there isnoeffectivedrag forhepaticfibrosis, andtherapyon theetiologiesisstill...
Hotta N, Ayada M, Okumura A, Ishikawa T, Sato K, Oohashi T, Hijikata Y, Murayama S, Ido M, Kakumu S, 2007.Noninvasive assessment of liver disease - measurement of hepatic fibrosis using tissue strain imaging. Clin Imaging.;31(2):87-92....
(redirected fromhepatic fibrosis) Thesaurus Medical Encyclopedia he·pat·ic (hĭ-păt′ĭk) adj. 1.Of, relating to, or resembling the liver. 2.Acting on or occurring in the liver. n. A drug that acts on the liver. [Middle Englishepatik, from Old Frenchhepatique, from Latinhēpaticu...
Summary Hepatic fibrosis is a reversible wound-healing response characterized by the accumulation of extracellular matrix (ECM) or "scar;" it follows chronic, but not self-limited, liver disease. The ECM components in fibrotic liver are similar, regardless of the underlying cause. Activation or tra...
Hedgehog (Hh) signalling regulates hepatic fibrogenesis. MicroRNAs (miRNAs) mediate various cellular processes; however, their role in liver fibrosis is unclear. Here we investigate regulation of miRNAs in chronically damaged fibrotic liver. MiRNA profiling shows that expression of miR-378 family members...
Endoplasmic reticulum (ER) stress is a major contributor to liver disease and hepatic fibrosis, but the role it plays varies depending on the cause and progression of the disease. Furthermore, ER stress plays a distinct role in hepatocytes versus hepatic stellate cells (HSCs), which adds to th...
Hepatic fibrosis, the major complication of virtually all types of chronic liver damage, usually begins in portal areas, and its severity has been correlated to liver progenitor cells (LPC) expansion from periportal areas, even if the primary targets of injury are intralobular hepatocytes. The aim...
Chronic liver disease is characterized by inflammation and fibrosis. Angiogenesis which leading to new vasculature may have prognostic value in disease progression. This study examined the implication of 5-lipoxygenase pathway and angiogenic factors in hepatic fibrosis progression and whether, the inhibition...