Significant fibrosis was present in 9.1% of patients, advanced fibrosis in 4.0%, and cirrhosis in 1.6%. Multivariate logistic regression showed that increasing age (odds ratio [OR], 1.06; p=0.003), presence of diabetes (OR, 2.62; p=0.019), elevated c- peptide (OR,...
This study aims to construct and validate noninvasive diagnosis models for evaluating significant liver fibrosis in patients with chronic hepatitis B (CHB). A cohort of 259 CHB patients were selected as research subjects. Through random grouping, 182 cases were included in the training set and 77...
markers of hepatic fibrosis is reviewed.Recent advances in noninvasive diagnosis are introduced and discussions on how to diagnose significant hepatic fibrosis are discussed.Combined application of serologic test and transient elastography is hopeful to improve the diagnostic accuracy.in liver fibrosis. ...
Utility of real-time shear wave elastography for assessing liver fibrosis in patients with chronic hepatitis C infection without cirrhosis: Comparison of l... To clarify the diagnostic impact of liver fibrosis except for cirrhosis identified using shear wave elastography (SWE) in chronic hepatitis C...
Significant Fibrosis Is Not Rare in Chinese Chronic Hepatitis B Patients with Persistent Normal ALTdoi:10.1371/journal.pone.0078672... - 《Plos One》 被引量: 0发表: 2013年 Re-appearance of hepatitis B virus following therapy with rituximab for lymphoma is not rare in Japanese patients with pas...
CCL20 has turned out to be a potential driver of inflammation and fibrosis in alcoholic hepatitis,however,the association of CCL20 with the severity of fibrosis in CHB is yet unclear.We aim to explore the value of serum CCL20 level in predicting the occurrence of significant liver fib...
and significant liver fibrosis as defined by a Metavir fibrosis score ≥ 2 in HBeAg-negative CHB patients that had a hepatitis B virus (HBV) DNA level ≥ 2,000 IU/ml and age ≥ 40 years or elevated alanine aminotransferase level between 1–2 times the upper limit of normal...
As of 2016, there is no evidence-based pathway to stratify the risk of chronic liver disease in a general population setting. Non-invasive tests of liver fibrosis might provide a mechanism for earlier diagnosis. These tests have been extensively validated in the hospital setting but their performa...
Results Significant liver fibrosis was detected through TE in 103 (12.7%) of 810 patients with normal serum ALT levels and in 91 (19.4%), 17 (18.7%) and 13 (5.8%) patients with chronic hepatitis B, chronic hepatitis C and nonalcoholic fatty liver disease, respectively. Univariate analysis ...
carboxyprothrombin (NX-DCP) could become a new noninvasive model to predict liver fibrosis in hepatitis C virus (HCV) related liver disease.We performed a prospective cohort study on a consecutive group of 101 patients who underwent liver biopsy for HCV-related liver disease at Kobe University ...