Initial Dose 75 to 100 units/kg (IV bolus over 10 minutes) Maintenance Dose Infants: 25 to 30 units/kg/hour;Infants < 2 months have the highest requirements (average 28 units/kg/hour)Children > 1 year of age: 18 to 20 units/kg/hour;Older children may require less heparin, similar...
Initial Dose:75 to 100 units/kg (intravenous bolus over 10 minutes) Maintenance Dose Infants:25 to 30 units/kg/hour; Infants < 2 months have the highest requirements (average 28 units/kg/hour) Children > 1 year of age: 18 to 20 units/kg/hour; Older children may require less heparin, ...
40units/kg 80units/kg IVPush (BolusDose) HighDose 9units/kg/hr 15units/kg/hr 16units/kg/hr IVInfusionRate (IVRate) LowDose n/a aPTTRange4 (2.1–3.0xcontrol) Nochange aPTTRange3 (1.5–2.0xcontrol) 30units/kg aPTTRange2 (1.2–1.5xcontrol) 60units/kg aPTTRange1 (<1.2xcontrol) IV...
A comparison of two methods of heparinizing hemodialysis set by continuous infusion and intermittent bolus effects on the rate of dialysis adequacy in hemodialysis patients A B S T R A C T Aims: Hemodialysis is one of the main treatments for patients with chronic renal failure. If performed ...
This study sought to determine whether an intravenous (IV) weight-based UFH dosing nomogram based on an 80-unit/kg bolus and 18-unit.kg(-1).h(-1) initial infusion rate achieves therapeutic anticoagulation [activated partial thromboplastin time (aPTT), 65-110 seconds] more rapidly than that ...
Low molecular weight heparin, such as enoxaparin, is typically administered in conjunction with the t-PA variant, such as tenecteplase, starting with a fixed IV bolus followed by weight adjusted subcutaneous (SC) injections. For example, the low molecular weight heparin such as enoxaparin can be ...
For example, the low molecular weight heparin such as enoxaparin can be administered as a single IV bolus, followed by SC injections. In a typical dosing regimen, a single IV bolus of about 30 mg low molecular weight heparin (e.g. enoxaparin) is followed by about 1 mg/kg SC injections ...
LBW was used to calculate initial bolus dose and infusion rate, and aPTT's were obtained at baseline and every 6 hours for 24 hours or until aPTT was therapeutic, whichever came first. Primary outcome was the percentage of patients achieving therapeutic aPTT within 24 hours. We also assessed...
volumes of diethylether at -20° C. Once synthesized, the peptides were purified by reversed-phase high performance liquid chromatography (HPLC) on a 2"×25 cm preparative reversed-phase column (Rainin, Dynamax). The flow rate was 17 ml/min. and the gradient was from 5% to 60% ...
The median initial infusion rate in patients with bleeding was 13.3U/kg/h, while in those without bleeding it was 11.4U/kg/h; p=0.012. An initial infusion rate >11.0 U/kg/h yielded an OR 1.95 (1.06鈥 3.59); p=0.03 for any bleeding event. Using IV heparin boluses neither increased...