Heparin Bolus or Infusion: Can We Draw a Conclusion?∗doi:10.1016/j.jacep.2016.02.002DavidE.HainesSDOSJacc Clinical Electrophysiology
When heparin 2,500 to 5,000 U was administered by intravenous bolus infusion to 13 fingers that had developed arterial thrombosis after replantation, complete survival was achieved in seven of 13 fingers. If fingers demonstrating partial necrosis were included, survival was obtained in 11 of 13 ...
Method: Two-hundred patients were enrolled in this study, 100 of whom received intravenous UFH (an initial bolus of 5000 U followed by continuous infusion of 1000 U/h) and 100 received enoxaparin subcutaneous injections of 1mg/kg twice daily for a minimum of 72 h. During their admission we...
, 17 in patients studied by these noninvasive methods, the diagnosis was also confirmed as soon as possible by venography. regimens patients in the intravenous heparin group received an initial bolus dose of 5000 us pharmocopeia units of heparin followed by continuous intravenous infusion of ...
Before angiography, we randomly allocated patients (1:1; stratified by age [<75 years vs ≥75 years] and presence of cardiogenic shock [yes vs no]) to heparin (70 U/kg) or bivalirudin (bolus 0·75 mg/kg; infusion 1·75 mg/kg per h). Patients were followed up for 28 days. The...
We aimed to identify attributing factors to the interindividual variabilities of the infusion rates in unfractionated heparin therapy. We included patients who required unfractionated heparin therapy to achieve the target APTT after cardiac surgery betwe
As soon as the diagnosis is suspected, an IV bolus of unfractionated heparin should be administered. In addition to anticoagulation, rapid initiation of ... N Kucher - 《Chest》 被引量: 190发表: 2007年 Thromboprophylaxis in the Cancer Patient Low molecular weight heparins and unfractionated hepar...
141 patients with unstable angina or suspected acute myocardial infarction without ST elevation were randomly assigned heparin (5000 units bolus then 15 units kg(-1) h(-1); n=5058) or hirudin (0.4 mg/kg bolus then 0.15 mg kg(-1) h(-1) infusion; n=5083) for 72 h in a double-...
1. A method comprising administering to a human patient in need of thrombolytic therapy an effective amount of a combination of a human tissue plasminogen activator (ht-PA) variant suitable for single-bolus administration, and a low molecular weight heparin. 2. The method of claim 1 wherein ...
Background Early guidance recommended a bolus of intravenous heparin at the beginning of leadless pacemaker (LP) implantation procedures. However, due to concern about bleeding complications, more recent practice has tended toward omitting the bolus and only running a continuous heparin infusion through...