Health Enhancement Program (HEP) for patients undergoing hemodialysis treatment who experience depression/anxiety symptoms. Our primary hypothesis was that BMI or HEP would decrease insomnia scores, as measured by Athens Insomnia Scale (AIS) and consolidation of sleep (ConDI) by actigraphy. Our ...
Chronic hepatitis C leads to fibrotic changes in the liver, and ultimately to cirrhosis, after the development of which, the patient has a high risk of developing hepatocellular carcinoma (HCC). The goal of HCV treatment has been to eradicate the infection, thereby terminating the chronic liver ...
Furthermore, we observed the rescue effect of GNP on the HepG2 cells after treatment with FXT. 2. Results 2.1. Effect of FXT-GNP Co-Treatment on the Cell Viability of HepG2 Cells The cell viability test of HepG2 cells was done in order to study the effect of FXT-GNP co-treatment ...
Furthermore, NOD1 agonist γ-D-Glu-mDAP (IE-DAP) treatment weakened the effect of Evo on suppression of NF-κB and MAPK activation and cellular proliferation of HCC. In an in vivo subcutaneous xenograft model, Evo also exhibited excellent tumor inhibitory effects via the NOD1 signal pathway. ...
2.10. Western Blot Analysis Cells and liver tissues were homogenized in RIPA buffer and then centrifuged at 10,000ˆ g, 4 ˝C for 10 min to obtain supernatant. Total protein concentration of each sample was determined using a BCA protein assay kit (Pierce, Rockford, IL, USA) according ...
The overall effects of this protein—when activated—on the lipid metabolism are to stimulate fatty acid oxidation and to block cholesterol and triglycerides synthesis [9,10]. Of current interest are the effects of naturally occurring compounds in the treatment and/or prevention of particular ...
Some reports have shown that unsaturated PLs provide numerous advantages in the prevention and treatment of cardiovascular disease, autoimmune disorders and neurological disease [17,18]. Marine PLs are much high in PUFAs [19]. Tsoupras et al. reported that several marine sources contain bioactive ...
LJE treatment suppressed lipid accumulation and intracellular triglyceride levels significantly in a concentration-dependent manner in HepG2 cells. Moreover, LJE significantly reduced the expression of sterol regulatory element binding protein 1-c, and its downstream genes, which are associated with ...
However, urushiol's sensitization combined with keratin or proteins in the cell membrane forms intact antigens, which attack the 4th-, 5th-, and 6th-position C atoms of benzene rings [10–13]. Novel urushiol derivatives have an anti-platelet agglutination activity. When tested in mice, they ...
2.2. Cell Treatment The cells were treated with 2-DG (0–10 mM), sodium oxamate (0–50 mM), or oligomycin (0–1.0 µg/mL; Santa Cruz, Dallas, TX, USA) for 24 h to test major metabolic pathways that are utilized by HepG2 cells. Each chemical was dissolved in DMSO and further...