Reliable objective approaches for the detection and characterization of sleep problems may turn out to be relevant for clinical screening of sleep. The values from the commercially available actigraphy processing software have usually been developed in healthy subjects with regular sleep patterns and are ...
Future studies of drug effects on cultured tumor cells should include a metabolomic component in order to understand the effect of the drugs on intermediary metabolism, especially if such studies are part of a high-throughput screening protocol within the drug discovery and development process [31,...
Changes in nuclear morphology of Evo-exposed cells were observed under a fluorescence microscope and featured a marked increase in the quantity of apoptotic chromatin condensation and nuclear fragmentation (Figure 1C). Meanwhile, flow cytometry analysis revealed that the apoptotic rate of HepG2 and ...
Some levopimaric derivatives act against respiratory viruses, the papilloma virus, and the hepatitis B and C viruses [22] (Figure S1). Notably, our research has indicated that the urushiol derivatives have a remarkable binding affinity with good scoring of histone deacetylase (HDAC)2 and HDAC8 ...