Level of intracellular reactive oxygen species (ROS) upon exposure to GO and CXYG.Hep G2 cells were exposed to increasing concentrations of GO (A) and CXYG (B) for 24 and 72 h (grey and black bars, respectively). Bars represent the mean of at least three independent experiments. Error ...
Future studies of drug effects on cultured tumor cells should include a metabolomic component in order to understand the effect of the drugs on intermediary metabolism, especially if such studies are part of a high-throughput screening protocol within the drug discovery and development process [31,...
Some levopimaric derivatives act against respiratory viruses, the papilloma virus, and the hepatitis B and C viruses [22] (Figure S1). Notably, our research has indicated that the urushiol derivatives have a remarkable binding affinity with good scoring of histone deacetylase (HDAC)2 and HDAC8 ...