Symptoms include blood clots, and red or brownish urine in the morning. Aplastic anemia (decreased production of blood cells) may lead to PNH, and people with PNH are at increased risk of acute myelogenous leukemia. Also called PNH.关键词:...
Heretofore, germline mutations in PIGA have not been described in humans and were presumed to be embryonic lethal on the basis of experiments in mice3 and in both murine19 and human embryonic stem cells.20 Attempts to create knock-out mice by traditional methods resulted in low levels of chim...