Hemoglobin CC Disease—Fact Sheet Definition ▪ Disorder caused by homozygous inheritance of the hemoglobin C mutation of the β-globin gene, resulting in red blood cell dehydration and mild chronic hemolysis Morbidity and Mortality ▪ Mild anemia, occasional symptoms referable to splenomegaly ...
To the Editor: An 11-year-old male with HbSC disease was admitted to the hospital with 3-day history of fever and left wrist pain. At admission he had significant pain and tenderness at the base of the first left metacarpal bone. He was up to date on his immunizations for Streptococcus...
On average, patients with hemoglobin SC disease have milder symptoms than do those with hemoglobin SS disease, and have more severe symptoms than do those with homozygous hemoglobin C disease. A number of other syndromes exist that involve a hemoglobin S compound heterozygous state. They are less...
If you don’t have these symptoms, you may get an A1c test to screen for diabetes as part of a routine doctor’s appointment, such as a physical. Several different factors help determine when you should first get your A1c tested and how often the test should be repeated. Keep in mind ...
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Hematuria in Sickle Cell C Disease: Precipitation by Acidosis and Correction by Dialysis The authors report on a patient with hemoglobin SC disease and acute renal failure in whom spontaneous hematuria occurred when the patient became acidotic and subsided when the acidosis was corrected by dialysis....
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Hyperglycemia affects axial signs in patients with Parkinson's disease through mechanisms of insulin resistance or non-insulin resistance To investigate the influence of hyperglycemia on motor symptoms, especially axial signs, and potential mechanisms related to insulin resistance (IR) in pat... R Wang...
Fat embolism is a known complication of bone marrow infarction in patients with sickle cell disease (hemoglobin SS and hemoglobin SC disease). We report a case of a 36-year-old woman with hemoglobin SC disease who presented with headache, nausea, and photophobia. The patient experienced hypoxic...
Role in disease Decrease of hemoglobin, with or without an absolute decrease of red blood cells, leads to symptoms of anemia. Anemia has many different causes, although iron deficiency and its resultantiron deficiency anemiaare the most common causes in the Western world. As absence of iron decr...