She has also a history of one normal pregnancy with no miscarriages and multiple splenic infarcts with resultant autosplenectomy. Her peripheral blood smear shows target cells, hemoglobin crystals, and microspherocytes. The article discusses homozygous hemoglobin C disease.EBSCO_AspBlood...
S/β°-thalassemia can differ from SS disease in that there may be less severe hemolysis and splenomegaly. S/β+-thalassemia (in which some normal β-globin chains are produced) is a milder disease and, in fact, is asymptomatic in many cases. Pathologic Features The peripheral blood sme...
Hemoglobin SC Disease (Sickle Cell Disease-SC) Combination of hemoglobin S and hemoglobin C. Hematology 1. Anemia –if present, usually mild, hemolytic. 2. Blood smear –many target cells; sickle cells occasionally seen. 3. Sickle cell preparations – positive. 4. Hemoglobin electrophoresis –SC...
~xamGation of the peripheral blood smear disclosed slight hypochromia and anisocytosis. The patient received a therapeutic trial of multivi- tamins with iron, but the anemia persisted. Over the next 5 years, the patient received several courses of oral elemental iron therapy, without improvement...
The typical rod-shaped HbC crystals in the peripheral blood smear often provide the diagnostic clue to the HbC disease. This case highlights that a careful... HS Arakelyan 被引量: 0发表: 2021年 Hemoglobin C/Korle-Bu Identified In A Patient With A Previous Diagnosis Of Hemoglobin S/C Disea...
Peripheral blood smear of all the patients displayed hypochromia, anisocytosis, poikilocytosis and target cells. The quantities of HbA 2+Hb CS were 4.3%～6.72%, while Hb A 2 2%. Gene analysis confirmed the diagnosis of homozygous Hb CS. Conclusion There was quite different in clinical ...
Peripheral blood smearPeripheral Blood SmearAnemia: Overview and Types LDHOsteosarcoma BilirubinBilirubinA bile pigment that is a degradation product of heme.Heme Metabolism Haptoglobin Genetic testingGenetic TestingDetection of a mutation; genotype; karyotype; or specific alleles associated with genetic traits...
Critical evaluation of peripheral smear in cases of anemia with high mean corpuscular hemoglobin concentration in children: A series of four cases.Critical evaluation of peripheral smear in cases of anemia with high mean corpuscular hemoglobin concentration in children: A series of four cases.doi:10.41...
(MCV). Low MCV, also known as microcytosis, is often the first indicator of thalassemia or thalassemia trait. A peripheral blood smear can also detect suspected hematologic disorders. Providers can see sizes, colors, and variations in the shape of erythrocytes. Peripheral smears can detect nuclei...
James Herrick first described sickle cell disease from observing the peripheral smear of a West Indian patient. The ocular manifestations of sickle cell disease were described by Cook in 1930 when he noticed retinal hemorrhages in a patient who died of subarachnoid hemorrhage. ...