Laboratory testing reveals sickle cells on peripheral blood smear and hemoglobin electrophoresis reveals a predominance of hemoglobin S. Treatment consists of immunizations for S pneumoniae, Haemophilus influenzae, hepatitis B, and influenza. Hemoglobin C disease is one-fourth as frequent as sickle cell ...
Crystal formation (classically, hexagonal-shaped crystals on peripheral blood smear) may result, which can lead to increased blood viscosity and cellular rigidity and shortened erythrocyte survival. Unlike sickle cell disease (SCD), Hb C does not cause linear intracellular polymerization of red cells ...
We report the first case of hemoglobin (Hb) SC disease with development of severe anemia induced by cold agglutinin hemolysis after Mycoplasma infection. Complete blood count (CBC) showed falsely decreased RBC count and hematocrit and falsely elevated MCV and MCHC. Peripheral blood smear showed RBC...
completeblood count(CBC) and peripheral smear findings. It is also important to note that drugs (hydroxyurea,sodium valproate, erythropoietin) and stresserythropoiesiscan also result in high HbF.Hydroxyureais used in sickle cell disease patients to increase the amount of HbF, the presence of which ...
~xamGation of the peripheral blood smear disclosed slight hypochromia and anisocytosis. The patient received a therapeutic trial of multivi- tamins with iron, but the anemia persisted. Over the next 5 years, the patient received several courses of oral elemental iron therapy, without improvement...
___ disease one, hgb barts, gamma alpha thalassemia silent carrier ___ alpha globin gene is deleted increase ___ (4 ___ chains) 2, anemia, hgb h alpha thalassemia minor (trait) ___ alpha genes deleted mild ___ on blood smear no ___ present 3, hgb barts, gamma...
Erythrocyte morphology was normal and no target cells were observed in the peripheral blood smear. On thin-layer starch gel electrophoresis at pH 8.6, this abnormal hemoglobin was found to be a fast moving component (Fig. 1). This component was separated from hemoglobin A and hemoglobin A2 by...
A peripheral blood smear revealed microcytic hypochromic red cells with some target cells. Hemoglobin electrophoresis showed a very high percentage of hemoglobin E, a very low percentage of hemoglobin A2, and normal proportions of hemoglobin A and hemoglobin F. A diagnosis ...
Cord blood may be requested for use as a positive control. Normal findings (Method: Microscopic examination of treated and stained peripheral blood smear) Less than 1% fetal cells present. Description The Kleihauer-Betke test is used to determine the degree of fetal-maternal hemorrhage (FMH) ...
Therefore, Heinz bodies are often detected only in a blood smear after splenectomy. Erythrocytes with Heinz bodies also have a high affinity to attach to the vascular endothelium. In some variants, oxidatively acting substances, drugs (Table 2), and infections trigger hemolytic crises. A classic ...