Definition noun, plural: T-helper cells A type of T lymphocyte that assists by activating antigen-presentingleukocytes, such asB cells,cytotoxic T cells and macrophages Supplement T lymphocytes, also called T cells, are a type oflymphocytes responsible for thecell-mediated immunity. TheTin T lymph...
Learn about helper T cells. Discover the helper T cell's function, helper T cell activation, the types of T helper cells, and how these cells are...
ResearchOpen Access29 Jun 2021Communications Biology Volume: 4, P: 820 Common clonal origin of conventional T cells and induced regulatory T cells in breast cancer patients The mechanisms that shape the regulatory T cell repertoire in patients with cancer are not completely understood. Here, the au...
In CIA mice, we observed elevated level of IL-21 on the CD4+ T cells, in line with the up-regulated of IL-21 mRNA expression. SM934 treatment induced pronounced decrease of the percentage of CD4+ IL-21+ cells (Fig. 6A). Accordingly, real-time PCR analysis revealed that IL-21 ...
Follicular T-helper cells:controlled localization and cellular interactions. Qi H,Chen X,Chu C,et al. Immunology and Cell Biology . 2014Qi H, Chen X, Chu C, Lu P, Xu H, et al. Follicular T-helper cells: controlled localization and cellular interactions. Immunol Cell Biol. 2014;92:28–...
Humoral immunity is vital for host protection, yet aberrant antibody responses can trigger harmful inflammation and immune-related disorders. T follicular helper (Tfh) cells, central to humoral immunity, have garnered significant attention for unraveling
As CD4+ T cells play a central role in the development of both humoral and cellular autoimmunity, defining critical cytokine targets in the development and maintenance of anti-MPO autoimmunity is essential for the application of novel biological therapies that target cytokines. A critical step in th...
First, a cDNA of segment 8 under the control of the T7 promoter was transfected in cells that have been previously infected with a temperature-sensitive helper virus mutant and the T7-VV. The NSP2 protein produced by the helper virus does not function at 39 °C, and therefore at this ...
The ratio of Th17 cells changed most notably with disease progression accompanied by an up-regulated level of IL-17. Moreover, the proliferative ability of AChR peptide-specific T cells and the anti-AChR antibody-secreting cells increased when stimulated by IL-17 in vitro. These findings ...
T-box transcription factor, T-bet, has a central role in the differentiation of T-helper (Th) progenitor cells to Th1 or Th2 effector cells, partly by regu... K Furuno,K Ikeda,S Hamano,... - 《Genes & Immunity》 被引量: 19发表: 2008年 Meta-analysis reveals conserved cell cycle tr...