Learn about helper T cells. Discover the helper T cell's function, helper T cell activation, the types of T helper cells, and how these cells are...
A T-helper cell is a type of T lymphocyte thathelpsor assists other white blood cells. For instance, it can stimulate aB cellto proliferate in order to generate clones. It does so when the B cell endocytose an antigen and process it to become antigenic peptides. The antigenic peptides ...
In subject area:Biochemistry, Genetics and Molecular Biology T-helper (Th) cells can be classified into Th1 cells, which produce interleukin (IL)-2 and interferon (IFN) γ and are involved in cellular immunity, and Th2 cells, which produce IL-4, IL-5 and IL-13 and are involved in humo...
SIRKKA KONTIAINEN, in Biology of the Lymphokines, 1979 Publisher Summary T-cells are considered to have a crucial role in the regulation of antibody and other immune responses. Some T-cells, helper cells, augment the antibody response of B-cells. Other T-cells, suppressor cells, diminish the...
ResearchOpen Access29 Jun 2021Communications Biology Volume: 4, P: 820 Common clonal origin of conventional T cells and induced regulatory T cells in breast cancer patients The mechanisms that shape the regulatory T cell repertoire in patients with cancer are not completely understood. Here, the au...
including the plasticity and heterogeneity of T cells, the tissue-specific effects, and the influence of cellular metabolism on cell fate decisions. Importantly, recent advances in cutting-edge approaches, especially systems biology tools, have contributed to new concepts and mechanisms underlying T-cell...
recognition of cells undergoing apoptosis as a direct result of infection induces unique development of this subset. As our knowledge of TH17 and T regulatory cells grows, we are building on a new framework for the understanding of effector T cell differentiation and the biology of CD4+T cell ...
Humoral immunity is vital for host protection, yet aberrant antibody responses can trigger harmful inflammation and immune-related disorders. T follicular helper (Tfh) cells, central to humoral immunity, have garnered significant attention for unraveling
Other transcription factors that play a role in Th17 development are IRF4, BATF, and AHR. IRF4 is thought to be upstream of RORγt, as the ability of naive CD4+T cells to upregulate RORγt expression is reduced in its absence, but its exact role in ...
Other transcription factors that play a role in Th17 development are IRF4, BATF, and AHR. IRF4 is thought to be upstream of RORγt, as the ability of naive CD4+T cells to upregulate RORγt expression is reduced in its absence, but ...