Hanna A, Shevde LA. Hedgehog signaling: modula- tion of cancer properies and tumor mircroenviron- ment. Cell Chem Biol 2017; 24: 252-280.Hanna A, Shevde LA (2016) Hedgehog signaling: modulation of cancer properies and tumor mircroenvironment. Mol Cancer 15: 24....
Onishi H,Katano M.Hedgehog signaling pathway as a therapeutic target in various types of cancer[J].Cancer Sci,2011,102(10):1756-1760.Onishi H and Katano M. Hedgehog signaling pathway as a therapeutic target in various types of cancer. Cancer Sci 2011; 102: 1756- 1760....
In this review, we assimilate data from recent studies to understand the mechanism of functioning of the hedgehog signaling pathway, role in cancer, its association in various solid malignancies and the current strategies being used to target this pathway for cancer treatment....
Understanding the role of hedgehog signaling in cancer is critically important for novel cancer therapeutics. The hedgehog pathway is a major pathway regulating cell differentiation, tissue polarity, stem cell maintenance and cell proliferation. It is known by now that activation of this pathway occurs...
Hedgehog signaling in cancer Cancer is one of the major causes of death in the world. Almost ten million cancer deaths were expected in 2020.185Cancers are highly burdensome diseases, which have negative physical and mental effects on patients, as well as serious economic consequences. HH signaling...
Understanding the role of hedgehog signaling in cancer is critically important for novel cancer therapeutics. The hedgehog pathway is a major pathway regulating cell differentiation, tissue polarity, stem cell maintenance and cell proliferation. It is known by now that activation of this pathway occurs...
Hedgehog signaling in prostate cancer Gastric cancers may harbor a subset of cells with cancer stem cell (CSC) properties, including chemotherapy resistance, and CD44 is a gastric CSC marker. T... J Xie - 《Future Oncology》 被引量: 41发表: 2005年 The Potential Role of Hedgehog Signaling in...
Victoria Campbell, Mhairi Copland Paul O#39;Gorman Leukaemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterninary and Life Sciences, University of Glasgow, Glasgow, UK Abstract: The stem cell paradigm was first demonstrated in hematopoietic stem cells. Whilst classically it...
HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity Curr. Biol., 17 (2007), pp. 165-172 View PDFView articleView in ScopusGoogle Scholar Corbit et al., 2005 K.C. Corbit, P. Aanstad, V. Singla, A.R. Norman, D.Y. Stainier, J....
Hedgehog signalingcancer stem cellsdevelopmental therapeuticsThe Hedgehog (Hh) pathway has been implicated in a wide variety of human tumors, and early ... AA Merchant,W Matsui - 《Clinical Cancer Research An Official Journal of the American Association for Cancer Research》 被引量: 604发表: 2010...