hepatitis C virus neutralizing antibodyBackground and Objectives At Japanese Red Cross (JRC) Blood Centers, all donated blood is screened for hepatitis C virus (HCV) by serological and nucleic acid amplification testing. Donor plasma that tested reactive for anti-HCV by serological test is ...
Plasma HCV antibody was detected using the Abbott Architect anti-HCV assay (Abbott GmbH & Co KG, Wiesbaden, Germany); Anti-HCV status of all positive anti-HCV were confirmed by HCV-RIBA assay (Wantai Biological Pharmacy), which utilizes recombinant proteins (Core, NS3, NS4 and NS5) immobili...
All samples were tested for HCV RNA, followed by analysis of anti-HCV screening test, RIBA and HCV nucleic acid test results. ResultsAnti-HCV ELISA results were reactive in 386 out of 527 intravenous drug users and non-reactive in 141. Among the 386 reactive antibody samples detected by ...
In this stuyd, 45 plasma samples from anti-HCV antibody-negative/HCV RNA-positive (window period) donors from Poland identified during nucleic acid testing (NAT) and 32 follow-up anti-HCV antibody-positive samples were tested retrospectively for HCV core antigen by Ortho Clinical Diagnostics first...
The HCV Ag/Ab assay detected HCV infection on average 21.6 days before the most sensitive antibody assay. The HCV Ag/Ab assay did not detect HCV ... S Laperche,NL Marrec,A Girault,... - 《Journal of Clinical Microbiology》 被引量: 175发表: 2005年 HCV antigen/antibody combination assay...
We provide the first in vivo evidence that HVR1 protects cross-genotype conserved HCV neutralisation epitopes, which advocates the possibility of using HVR1-deleted viruses as vaccine antigens to boost broadly reactive protective nAb responses. 展开 关键词: HCV HEPATITIS C DOI: 10.1136/gutjnl-...
Changes in Hepatitis C Virus (HCV) Antibody Status in Patients with Chronic Hepatitis C after Eradication of HCV Infection by Interferon Therapy BACKGROUND: Changes in hepatitis C virus (HCV) antibody status were followed for 10 years after the eradication of HCV by interferon (IFN) therapy in ...
(a) The levels of selected HuR target mRNAs in control and SUDHL6- NS3/4A (mass culture) cells were detected by ribonucleoprotein (RNP)-IP with anti-HuR antibody, followed by RT–qPCR analysis. Data show mean and s.d. from at least three separate experiments. * and ** indicate values...
median 41 years) and 33 with a self-limited outcome (aged 23–70 years; median 40 years), with clinical, biochemical and virological evidence of acute HCV infection (transaminase levels at least ten times higher than the upper limit of the normal range, anti-HCV antibody, and HCV-RNA posit...
All specimens that were reactive or borderline reactive for either antigen or antibody were confirmed by quantitative HCV PCR (COBAS® AmpliPrep/ COBAS® TaqMan® HCV, v2.0, Roche Basel, Switzerland). HIV and Syphilis rapid test results were not entered into the...