Table 2 Exposure risks with significant associations comparing HCV antibody positive and negative men who have sex with men from Zurich, stratified by HIV diagnosis Full size tableIn the univariable analysis among non-HIV-diagnosed MSM (Table 2), being tattooed was marginally associated with HCV ...
dual infection, since viral proteins are also expressed in single infection if they inhibited the immune response. We believe that the HBV/HCV dual infection placed a heavier burden on the immune system of the host, and that the antibody production has to deal with two viral infections, which ...
Anti-HCV positive, but HCV RNA-negative, subjects were frequently observed in group A (P < 0.01) and in female (P < 0.05). We concluded that (1) the high titer of antibody against each epitope may reflect the presence of HCV RNA; (2) the natural elimination of HCV may have occurred...
Perspective study of the antibody response to hepatitis C virus (HCV) antigens in acute nonA-nonB viral hepatitisHumansHepatitis BHepatitis DSubstance Abuse, IntravenousAcute DiseasePrevalenceCarrier StateChronic DiseaseGreeceHepatitis B Surface Antigens...
503 \\{HCV\\} \\{NEUTRALIZING\\} \\{ANTIBODY\\} \\{RESPONSE\\} \\{DURING\\} \\{SPONTANEOUS\\} \\{AND\\} TREATMENT-INDUCED \\{VIRAL\\} \\{CLEARANCE\\} \\{OF... X.V. Thomas and R. Molenkamp and S.M. Koekkoek and J.T.M. van der Meer and M. Prins and S. Merat...
Currently, it is recommended that infants at risk for perinatal transmission are tested with an antibody test at 18 months [36]. If positive at that time, they are presumed infected. Subsequently, if a child is diagnosed with HCV, it is recommended that the child be followed to 3 years ...
Recent HCV infection (i.e., acute or early chronic infec- tion) was defined by an initial positive anti-HCV anti- body test within 6 months of enrolment and either 1) a negative anti-HCV antibody test within two years prior to the initial positive anti-HCV antibody test or 2) acute ...
viral-infected cells. In 1986, the first murine mAb muromonab-CD3 (murmonabCD3, clone OKT3), which treats rejection of organ transplant, was approved by United States FDA, but there are limitations of its application, which caused by its human-anti-mouse antibody (HAMA) reaction in the ...
positive correlations with nAb breadth (R = 0.372,P = 0.021;R = 0.580,P < 0.001, respectively) (Fig.2E,F). There was no correlation between the frequency of CXCR3−cTfh cells and antibody breadth (Fig.2G). The ratio of CXCR3+/CXCR3−cTfh cells also showed a...
which was shown to help endocytosis of the virus. Viral entry could be prevented in a number of cell types using an anti-LDL monoclonal antibody [17]. Mannose binding proteins (DC-SIGN and L-SIGN) have been suggested as to have interactions with E2 but their contribution to viral entry is...