Alter et al - Guidelines for Laboratory Testing and Result Reporting of Antibody to Hepatitis C VirusRIBA(以(以 Chiron为例)为例) 两个以上条带(1+)为阳性Anti-HCV检测灵敏度也是不能忽略检测灵敏度也是不能忽略(70天)天)DNA 阳性阳性3rd gen1st gen2nd gen不同的不同的3rd试剂试剂第三代试剂之间也...
Peeling, R.W.; Mabey, D.; Herring, A.; Hook, E.W., 3rd. Why do we need quality-assured diagnostic tests for sexually transmitted infections? Nat. Rev. Microbiol. 2006, 4, 909–921. [CrossRef] [PubMed] 21. Hawkins, A.; Davidson, F.; Simmonds, P. Comparison of plasma virus ...
保护基根据欲进行保护的官能基的种类而异,例如对羟基进行保护时优选使用叔丁基二苯基甲硅烷基、四氢吡喃基、甲氧基甲基、苄基、三甲基甲硅烷基、对-甲氧基苄基、叔丁基二甲基甲硅烷基等基。另外,对羧基进行保护时可使用例如Protective Groups in Organic Synthesis,the 3rd edition(John Wiley& Sons Inc,1999年发...
[46] Lo Re 3rd V, Kallan MJ, Tate JP, et al. Hepatic decompensation in antiretroviral-treated patients co-infected with HIV and hepatitis C virus compared with hepatitis C virus-monoinfected patients: a cohort study[J]. Ann Intern Med,2014, 160(6):369-379.[47] World Health Organization...
第一组研究对患有局部进行性或者转移期胰腺癌的患者就吉西他滨和5-FU进行了多中心、预期双盲随机对比(Burris,HA.,3rd等人,ImprovementsIn Survival And Clinical Benefit With Gemcitabine AsFirst-Line Therapy For Patients With Advanced Pancreas CancerA Randomized Trial.J Clin Oncol,1997.15(6)2403-13)。每个...
Appleby TC, Perry JK, Murakami E, Barauskas O, Feng J, Cho A, Fox D 3rd, Wetmore DR, McGrath ME, Ray AS, Sofia MJ, Swaminathan S, Edwards TE. Viral replication. Structural basis for RNA replication by the hepatitis C virus polymerase. Science. 2015;347:771–5. Article CAS PubMed...
Tai VW, Garrido D, Price DJ, Maynard A, Pouliot JJ, Xiong Z, Seal 3rd JW, Creech KL, Kryn LH, Baughman TM, et al. Design and synthesis of spirocyclic compounds as HCV replication inhibitors by targeting viral NS4B protein. Bioorg Med Chem Lett. 2014;24(10):2288–94. Article CAS ...
3、率 3.2% 3千千8百万感染者百万感染者Evolution of anti-HCV antibody assaysCE1E2NS2NS3NS4Bp7NS4ANS5ANS5Bstructural non-structural c22c33c100NS55-1-11st generation EIA2nd generation EIA3rd generation EIA/CIA5-UTR3-UTR1990*1992*1996* Years in which the assays were approved by FDA检测模式的改进...
(1995),w.h.freeman,newyorkn.y.;gait,oligonucleotidesynthesis:apracticalapproach(2002),irlpress,london;nelsonandcox,lehninger,principlesofbiochemistry(2000)3rded.,w.h.freemanpub.,newyork,n.y.;berg,etal.,biochemistry(2002)5thed.,w.h.freemanpub.,newyork,n.y.;d.weir&c.blackwell,eds.,...
an E1 protein having the amino acid sequence from the 192nd to the 383rd amino acid, an E2 protein having the amino acid sequence from the 384th to the 746th amino acid, a P7 protein having the amino acid sequence from the 747th to the 809th amino acid, an NS2 protein having the ...