Alter et al - Guidelines for Laboratory Testing and Result Reporting of Antibody to Hepatitis C VirusRIBA(以(以 Chiron为例)为例) 两个以上条带(1+)为阳性Anti-HCV检测灵敏度也是不能忽略检测灵敏度也是不能忽略(70天)天)DNA 阳性阳性3rd gen1st gen2nd gen不同的不同的3rd试剂试剂第三代试剂之间也...
Appleby TC, Perry JK, Murakami E, Barauskas O, Feng J, Cho A, Fox D 3rd, Wetmore DR, McGrath ME, Ray AS, Sofia MJ, Swaminathan S, Edwards TE. Viral replication. Structural basis for RNA replication by the hepatitis C virus polymerase. Science. 2015;347:771–5. Article CAS PubMed...
2018. 10. Yehia BR, Schranz AJ, Umscheid CA, Lo Re V 3rd. The treatment cascade for chronic hepatitis C virus infection in the United States: a systematic review and meta-analysis. PLoS One. 2014;9(7):e101554. 11. Luetkemeyer AF, Wyles DL. CROI 2018: highlights of viral hepatitis....
Tai VW, Garrido D, Price DJ, Maynard A, Pouliot JJ, Xiong Z, Seal 3rd JW, Creech KL, Kryn LH, Baughman TM, et al. Design and synthesis of spirocyclic compounds as HCV replication inhibitors by targeting viral NS4B protein. Bioorg Med Chem Lett. 2014;24(10):2288–94. Article CAS ...
[46] Lo Re 3rd V, Kallan MJ, Tate JP, et al. Hepatic decompensation in antiretroviral-treated patients co-infected with HIV and hepatitis C virus compared with hepatitis C virus-monoinfected patients: a cohort study[J]. Ann Intern Med,2014, 160(6):369-379.[47] World Health Organization...
HCV病毒学特征 RNA基因组衣壳 黄病毒属1有衣壳蛋白包裹2已知6种基因型,>80个亚型3病毒基因组具有高度变异性3 –形成不同基因构成的病毒亚群或准种1,4 增殖速度:1012个/天2 病毒颗粒 核心蛋白 1.PurcellR.NIHConsensusConferenceonHepatitisC.1997;2.NeumannA,etal.Science1998;282:103;3...
2018. 10. Yehia BR, Schranz AJ, Umscheid CA, Lo Re V 3rd. The treatment cascade for chronic hepatitis C virus infection in the United States: a systematic review and meta-analysis. PLoS One. 2014;9(7):e101554. 11. Luetkemeyer AF, Wyles DL. CROI 2018: highlights of viral hepatitis....
April 3rd 2025 OncLive’s FDA Approval Report: The Regulatory Rundown for March 2025 May 24th 2024 Oncology Experts Preview Top Abstracts From the 2024 ASCO Annual Meeting April 1st 2025 Local Excision Possible for More Rectal Cancer Patients, Fox Chase Cancer Center Study Finds April 1st 2025 ...
an E1 protein having the amino acid sequence from the 192nd to the 383rd amino acid, an E2 protein having the amino acid sequence from the 384th to the 746th amino acid, a P7 protein having the amino acid sequence from the 747th to the 809th amino acid, an NS2 protein having the ...
W. Greene, Protective Groups in Organic Synthesis, 3rd edition, John Wiley & Sons, Inc. 1999. It is understood that the names and illustration used in this Application to describe compounds of Formula (I) are meant to be encompassed all possible protected derivatives thereof. “Therapeutically ...