There- fore, to assess whether SOAT1 is related to risk of HCC occurrence, we explored the association of SOAT1 gene missense variants with HCC susceptibility in a case- control design of biopsy proven HCC patients and healthy controls. To our knowledge, this is the first study to report a...
We finally compared its performance with that of the HBV DNA-free WHO treatment criteria intended to be used in LMICs,13 and the risk estimation for HCC in chronic hepatitis B (REACH-B) score including HBV DNA as one of the variables.14 Patients and methods Derivation dataset From December ...
Chronic hepatitis B is a severe liver disease caused by hepatitis B virus (HBV) infection. Covalently closed circular DNA (cccDNA), a super-spiralized, double-stranded form of the HBV genome, is the major determinant of viral persistence. CRISPR/Cas9 nuc