Chronic hepatitis B (HBV) infection is a major risk factor for hepatocellular carcinoma (HCC). Most HCCs complicate the evolution of an active or inactive cirrhosis. However, some tumors occur on livers with minimal histological changes; the prevalence of such cases varies from one geographical ...
Chapter 3 Role of Anti-Viral Therapy on Hepatitis B Virus ( HBV )-Related Hepatocellular Carcinoma ( HCC )doi:10.5772/55551 C Chong,G Wong,V Wong,... 被引量: 0发表: 2013年 The Emerging Role of Ground Glass Hepatocytes and Hepatitis B Virus Pre-S Mutants in Anti-Viral Therapy and HBV...
Hepatitis B virus (HBV) is one of the major risk factors of hepatocellular carcinoma (HCC). Increasing evidence indicates that microRNA (miRNA)–mRNA axis is involved in HCC. However, a comprehensive miRNA–mRNA regulatory network in HBV-related HCC is still absent. This study aims to identify...
Conclusion In patients with advanced HBV-related HCC treated with sorafenib, a high baseline HBV load was an adverse prognostic factor for survival. However, survival was significantly improved with the use of antiviral therapy. 展开 关键词: antiviral therapy hepatitis B hepatocellular carcinoma ...
Interestingly, Wen and Han, et al.20 found that HCC is independently associated with an increase in miR-18520. miR-185 levels are increased in both liver fibrosis and HCC. Since liver fibrosis can progress to HCC, we speculate that there is an elevation in miR185 levels upon transition ...
In a series of 325 HBV chronically infected children observed over an 18-year period, three developed HCC. These three children were born in southern Italy, a region characterized by a high endemic HBV infection rate; each had been infected perinatally, developed an acute hepatitis, and became ...
HBV‐related HCCHCClncRNASNPBackground Long nonヽoding RNA (lncRNA) plays an essential role in hepatitis B virus‐related hepatocellular carcinoma (HBV‐related HCC) occurrence and development. Single nucleotide polymorphism (SNP) may affect HBV‐related HCC susceptibility by altering the function of...
(YTHDF2), plays a critical role in the HCC progression. However, the function and regulatory mechanisms of YTHDF2 in HBV-related HCC remain largely elusive. Here, we discovered that YTHDF2 O-GlcNAcylation was markedly increased upon HBV infection. O-GlcNAc transferase (OGT)-mediated O-...
CONCLUSIONS: We should pay more attention to patients with MetS-HCC perioperatively due to the high rate of surgical complications. Nevertheless, curative treatment should be provided to patients with MetS. 展开 关键词: Hepatectomy Metabolic syndrome Hepatitis virus B Hepatocellular carcinoma Surgery ...
Hepatitis B virus (HBV) infection is a global health problem that cannot be ignored [1] and contributes to more than half of hepatocellular carcinoma (HCC) cases worldwide [2,3]. Although effective preventive vaccines have become available in recent decades, chronic HBV infection remains difficult...