综述306 2016 年 22 期 关于 HBA1 和 HBA2 基因的 2 种重组形式报道 何云英 郭晓玲 暨南大学,广东 广州 510632 摘要:目的:报道 HBA1 和 HBA2 地中海贫血基因间的 2 种重组形式;方法:通过单管多重裂口 PCR 法和 Sanger 测序法分别检测 HBA1 及 HBA2 地中海贫血基因上缺失和突变;结果:在 1514 例样本...
HBA1的详细信息,包括基因名称,代码,染色体位置,相互作用关系和通路,简述为位于16号染色体上的人α珠蛋白基因簇跨越大约30 kb和包括七个基因位点:5‘-泽塔 - pseudozeta - 亩 - pseudoalpha-1 - α-2 - α-1 - THETA - 3‘。α-2(HBA2)和α-1(HBA1)编码
Western Blot analysis of HBA2 using a HBA2 Polyclonal antibody (Product # PA5-97820) at a concentration of 2 µg/mL. Lane 1: HepG2 whole cell lysate. Lane 2: Hela whole cell lysate. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:10,000 dilution. Observed ...
基因别名:HBA-T3; HBA1; HBA2; HBH UniProt ID:(Human) P69905 Entrez Gene ID:(Human) 3039 功能 peroxidase activityoxygen transporter activityiron ion bindingprotein bindingoxygen bindingheme bindinghaptoglobin binding 参与通路 receptor-mediated endocytosispositive regulation of cell deathoxygen transportbica...
Edmond S. K. MaTaylor & FrancisHemoglobinNovel point mutation of the alpha2-globin gene (HBA2) and a rare 2.4 kb deletion of the alpha 1-globin gene (HBA1), identified in two chinese patients with Hb H disease. SoC C,Chan A Y,Ma ES. Hemoglobin . 2014...
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slight...
rdb等方法,主要检测常见的3个hba2和17个hbb基因突变位点。这些检测试剂盒主要有以下几个方面局限:1、无法实现在同一体系内同时检测缺失型和非缺失型α ‑ 、β ‑ 和δ ‑ 地中海贫血相关突变检测;2、只检测常见的地贫突变,覆盖范围有限,容易造成漏检,比如罕见的hba1/2、hbb和hbd基因点突变,以及anti ...
The absence of the HBA1-F gene in alpha-thalassemia patients was observed. Demographic analysis showed no significant age or gender differences between the two groups. Thalassemia patients, analyzed alongside the control group, exhibit elevated HbA2 levels (2.7%–6.6%) and increased HbF levels (...
Western Blot analysis of HBA2 using a HBA2 Polyclonal antibody (Product # PA5-97820) at a concentration of 2 µg/mL. Lane 1: HepG2 whole cell lysate. Lane 2: Hela whole cell lysate. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:10,000 dilution. Observed ...
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slight...