[4]Law H Y,Luo H Y,Wang W,et al.Determining the cause of patchwork hba1 and hba2 genes:Recurrent gene conversion or crossing over fixation events[J].Haematologica,2006,91(3):297-302. [5]Borgio J F,AbdulAzeez S,Al-Nafie A N,et al.A novel hba2 gene conversion in cis or trans:...
Clinical chemistry and laboratory medicine: CCLMPetropoulou M, Poula A, Traeger-Synodinos J, et al. Screen- ing non-deletion c~-thalassaemia mutations in the HBA1 and HBA2 genes by high- resolution melting analysis[J]. Clin Chem Lab Med, 2015,53(12):1951-1959....
HBA1的详细信息,包括基因名称,代码,染色体位置,相互作用关系和通路,简述为位于16号染色体上的人α珠蛋白基因簇跨越大约30 kb和包括七个基因位点:5‘-泽塔 - pseudozeta - 亩 - pseudoalpha-1 - α-2 - α-1 - THETA - 3‘。α-2(HBA2)和α-1(HBA1)编码
HBA1, the gene encoding α1-globin, and HBA2, the gene encoding α2-globin, are the two genes most commonly associated with α-thalassemia. Molecular... R Galanello,A Cao - 《Genetics in Medicine Official Journal of the American College of Medical Genetics》 被引量: 16发表: 2014年 绵羊...
alpha chains combine with delta chains to constitute HbA-2,which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin.Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1;some nondeletion alpha thalassemias have ...
Summary The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These ge...
The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult ...
alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias ha...
Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008] Inmunógeno A synthesized peptide derived from human Hemoglobin subunit alpha (HBA1) (...
alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias ha...