Sulfoxide-alkene hybrids: A new class of chiral ligands for the Hayashi-Miyaura reaction - Thaler, Guo, et al.Sulfoxide-alkene hybrids: a new class of chiral ligands for the Hayashi-Miyaura reaction. Thaler Tobias,Guo Li-Na,Steib Andreas K,Raducan Mihai,Karaghiosoff Konstantin,Mayer Peter,...
T. Hayashi found that N. Miyaura's Rh(I)-catalyzed conjugate addition of aryl- or alkenylboronic acids to α,β-enones can be converted to a highly enantioselective process by the use of the chiral BINAP ligand.50Hayashi's model of the pre-transition state assembly and the reaction pathway...
clavine alkaloidsRh(I)-catalyzed conjugate additionWe report the development of the diastereoselective rhodium(I)‐catalyzed intramolecular conjugate addition (Hayashi‐Miyaura reaction) of robust and easily handled 4‐pinacolboronic ester D‐tryptophan derivatives tethering an activated alkene as the ...