2.A kit for the early identification of fat deposition in bovines, wherein said kit comprises:(i) primers for amplifying a portion of a DDEF1 gene sequence, comprising a first primer molecule comprising the nucleotide sequence of SEQ ID NO: 1, a second primer molecule comprising the nucleot...
Mouse having mutations including (i) a mutation in both alleles of protein kinase, DNA-activated, catalytic polypeptide (Prkdc) gene, (ii) a mutation in both alleles of the gene encoding for the interleukin-2 receptor (IL-2)-gamma -chain, (iii) a mutation in at least one allele of the...
Mouse having mutations including (i) a mutation in both alleles of protein kinase, DNA-activated, catalytic polypeptide (Prkdc) gene, (ii) a mutation in both alleles of the gene encoding for the interleukin-2 receptor (IL-2)-gamma -chain, (iii) a mutation in at least one allele of the...
The term “homozygous” indicates that identical alleles reside at the same loci on homologous chromosomes. In contrast, “heterozygous” indicates that different alleles reside at the same loci on homologous chromosomes. A transgenic animal may be homozygous or heterozygous for a transgene. The term...
two amino acids which are identical and in the sme relative positions and there should be a number, i.e. at least two and preferably at least three amino acids, at corresponding positions, which are not identical but have similar reactivities. In general there should be fewer than 20 ...
Antibodies consist of two identical light polypeptide chains of molecular weight approximately 23,000 daltons (the “light chain”), and two identical heavy chains of molecular weight 53,000-70,000 (the “heavy chain”). The four chains are joined by disulfide bonds in a “Y” configuration ...
A preferred condition is whether the peptide has a high probability of being bound with high affinity to the MHC molecule of the alleles of the given host and in the competitive context of its protein of origin while at the same time displaying a specific motif for recognition by a T-cell...
Allele. An “allele” is any of one or more alternative form of a gene, all of which relate to one trait or characteristic. In a diploid cell or organism, the two alleles of a given gene occupy corresponding loci on a pair of homologous chromosomes. Amplicon. A piece of DNA formed as...
Meldrum, “Automation for Genomics, Part Two: Sequencers, Microarrays, and Future Trends”, Genome Research, 10:1288-1303, 2000. Miyagishi M, and Taira K. (2002). U6-promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells. Nature...
Thus, the 20S core is identical at its two ends. The x-ray structure of the archaebacterial proteasome has recently been resolved and was shown to contain a narrow pore in each α ring, and a large central cavity formed by the β rings. Accordingly, the central cavity is not exposed ...