HAS2-AS1和USF1在胶质瘤组织和细胞中都有高表达,USF1可以与HAS2-AS1启动子区域结合,激活HAS2-AS1的转录,从而促进胶质瘤细胞的迁移和侵袭。本研究揭示了HAS2-AS1在胶质瘤中高表达的机制,作为促癌因子,HAS2-AS1可能成为胶质瘤潜在的诊断标记物...
In vitro studies suggested that knocking down HAS2‐AS1 expression inhibited glioma cell viability, migration, and invasion through phosphoinositide 3‐kinase/protein kinase B signaling pathway. In conclusion, HAS2‐AS1 may be considered as a predictor for clinical outcome and a potential therapeutic ...
一、写出下列画线的词是助动词还是实义动词并写出词义,无词义的写“无”。as1. She has long hair.词性:词义:2. Dogs have two ears
as soon as as well as as long as1. Zhang Hua has known my brother as well as me.2. You can phone me at work as long as_ you are free.3. As soon as I open the door, we can smell the delicious food in the kitchen. 相关知识点: 试题来源: 解析 答案见上 反馈 收藏 ...
细胞凋亡氧化应激目的探究长链非编码RNA透明质酸合成酶2反义转录本1(lncRNA HAS2-AS1)基因对口腔鳞癌细胞自噬性死亡和氧化应激的影响.方法采用RNA干扰技术沉默CAL-27人口腔鳞癌细胞HAS2-AS1基因,应用实时荧光定量PCR检测HAS2-AS1的表达,Western blot法检测微管相关蛋白1轻链3BⅠ(LC3BⅠ),LC3BⅡ,自噬相关基因7(ATG7...
However, the role of lncRNA hyaluronan synthase 2 antisense 1 (HAS2-AS1) in the NSCLC tumorigenesis is not clear. Here, we investigate the role and mechanism of HAS2-AS1 in the NSCLC tumorigenesis. In the NSCLC tissue and cells, HAS2-AS1 was found to be up-regulated, which, in turn...
Downstream mechanistic studies revealed that HAS2-AS1 stabilizes the expression of its sense gene HAS2 via RNA/mRNA heteroduplex formation. Knockdown of HAS2-AS1 led to reduced production of hyaluronic acid (HA) and aggrecan, two major constituents of the endothelial glycocalyx (EG), resulting ...
结果1 题目 for example,such as1. Mary has many hobbies(业余爱好),such as swimming and running.2. Children should eat less junk food.For example , they should eat fewer hamburgers. 相关知识点: 试题来源: 解析 答案见上 反馈 收藏 ...
百度试题 结果1 题目(G)for example, such as1. He has been to many countries,America,Japan and Germany.2., he is a good student. 相关知识点: 试题来源: 解析 (G)1. such as 2. For example 反馈 收藏
HAS2‐AS1tumorigenesisGlioblastoma multiforme (GBM) is a refractory tumor with poor prognosis and requires more effective treatment regimens. It has been confirmed that long noncoding RNAs (lncRNAs) substantially regulate various human disease including GBM. However, the biological roles and its ...