Bayesian test procedures for Hardy–Weinberg equilibrium for the autosomes have been described, but Bayesian work on the X chromosome in this context is lacking. This paper gives the first Bayesian approach for testing Hardy–Weinberg equilibrium with biallelic markers at the X chromosome. Marginal ...
1 based on the logarithm log w^ of the estimated allelic odds ratio, the upper a/2 quantile (za/2) of the standard normal distribution, and observed frequencies nij's in Table 1 (Balding et al. 2001), assumes the Hardy–Weinberg equilibrium (HWE) in study populations. 123 J Hum Genet...
Except for the natural and orthogonal interactions approach (NOIA) method, current methods to construct relationship matrices assume Hardy鈥揥einberg equilibrium (HWE). The objective of this paper is to apply vector algebra to center and scale relation ship matrices under non-HWE conditions, ...