Komatsu, "Relationship between the antidiarrhoeal effects of Hange-Shashin-To and its active components," Phytotherapy Research, vol. 13, no. 6, pp. 468-473, 1999.Kase, Y., Saitoh, K., Makino, B., Hashimoto, K., Ishige, A., Komatsu, Y.; Relationship between the antidiarrhoeal ...
All 4 of the patients who did not receive Hange-shashin-to experienced diarrhea above Grade 1 within 6 days of starting therapy. The rate of diarrhea differed significantly between the patients receiving and not receiving Hangeshashin- to. In conclusion, preventive administration of Hange-shashin-...
We attempted to characterize the antidiarrheal action of Hange-shashin-to (TJ-14), a kampo medicine, by comparing its action with that of loperamide. The oral administration of TJ-14 caused the dose-dependent suppression of castor oil-induced diarrhea at 250 to 1000 mg/kg. No significant repr...
Mori K, Kondo T, Kamiyama Y, Kano Y, Tominaga K (2003) Preventive effect of Kampo medicine (Hangeshashin-to) against irinotecan-induced diarrhea in advanced non-small-cell lung cancer. Cancer Chemother Pharmacol 51: 403-406.Mori K,Kondo T,Kamiyama Y,et al.Preventive effect of Kampo ...
P-226HGCSG 1301: A Multicenter, Double-Blind, Randomized control phase II trial comparing Hange-shashin-to versus placebo to prevent diarrhea in patients with metastatic colorectal cancer under IRIS/Bev second-line treatmentdoi:10.1093/annonc/mdy151.225Nakamura, M...
Journal of Clinical Medicine Article Effect of Hangeshashin-To (Japanese Herbal Medicine Tj-14) on Tolerability of Irinotecan: Propensity Score and Instrumental Variable Analyses Hirokazu Urushiyama 1 ID , Taisuke Jo 1,2,* ID , Hideo Yasunaga 3, Nobuaki Michihata 2, Hayato Yamana 2, Hiroki ...
The patients gargled with 2.5 g Hange‐Shashinto‐To mixed with tap water 3 times a day during and after chemoradiation period, prohibiting eating and drinking for 30 minutes after the gargling. Results: Two patients started gargling with Hange‐Shashin‐To after grade III...