1946Background: A new grading system for graft-versus-host disease (GVHD) severity was established by the National Institute of Health (NIH)-consensus criteria (NCC) which was introduced since 2007. However, prognostic implications of the NCC grading system on GVHD-specific survival (GSS) are ...
Performance of a new clinical grading system for chronic graft-versus-host disease: a multicenter study. Blood 2003; 102: 802–809. Article CAS PubMed Google Scholar Flowers ME, Martin PJ . Evaluation of thalidomide for treatment or prevention of chronic graft-versus-host disease. Leuk ...
GvHD diagnosis is complicated, and grading and staging vary depending upon the tool and transplant centre involved. For the majority of patients who go on to develop GvHD, corticosteroids remain the first-line treatment for both acute and chronic forms of the disease. Recipients that are ...
(ml diarrhoea/day) <500 ml/day >500–999 ml/day or persistent nausea with histological evidence stomach/duodenum 1000–1500 ml/day >1500 ml/day Severe abdominal pain with or without ileus Acute GvHD clinical grading modified Glucksberg/ keystone criteria Grade Skin Liver Gut 0 None ...
gvhd在临床上被诊断,在可能时通过活检在病理学上确认,并且根据如先前所述的历史共同标准进行分类(参见rowlingspa,przepiorkad,kleinjp等,《用于将急性移植物抗宿主病分级的ibmtr严重程度指数:与glucksberg等级进行回顾性比较(ibmtrseverityindexforgradingacutegraft-versushostdisease:re-trospectivecomparisonwithglucksberggr...
Response of 443 patients to steroids as primary therapy for acute Graft-Versus-Host Disease: comparison of grading systems. Biol Blood Marrow Transplant 2002; 8: 387–394. Article CAS PubMed Google Scholar MacMillan ML, Robin M, Harris AC, DeFor TE, Martin PJ, Alousi A et al. A ...
1994 consensus conference on acute GVHD grading. Bone Marrow Transplant. 1995;15(6):825–8. CAS PubMed Google Scholar Horwitz ME, Sullivan KM. Chronic graft-versus-host disease. Blood Rev. 2006;20(1):15–27. Article PubMed Google Scholar Gooley TA, Leisenring W, Crowley J, Storer BE...
GI-aGvHD was graded according to the Lerner grading system79 whereas clinical GvHD at the time of biopsy was graded according to the Glucksberg grading system37. For data analyses, biopsies were grouped according to GvHD severity into mild (clinical GvHD score in the gastrointestinal tract 0-1)...
For example, in a study evaluating a clinical grading system for cGVHD,4 extensive skininvolvement, thrombocytopenia, and progressive onset of cGVHD were identified to be significant predictors of disease-free survival. In the present study, disease-free survival in the 4 RGs was 82%, 68%, 34...
1994 Consensus Conference on acute GVHD grading. Bone Marrow Transplant 1995; 15: 825–828. 9 Deeg HJ, Antin JH. The clinical spectrum of acute graft-versus-host disease. Semin Hematol 2006; 43: 24–31. 10 Filipovich AH, Weisdorf D, Pavletic S, Socie G, Wingard JR, Lee SJ et al...