Still, the well-characterized role of microbiota in neurogenesis and neurodevelopment45 moderates the translational relevance of these findings for adult conditions. An alternative to the GF model approach is the use of broad-spectrum antibiotics to induce transient changes on the composition and ...
Inflammation is a common feature of both obesity and cancer; however, the origin of this inflammation has been largely debated. Over the past decade, growing evidence has shown that the composition of the gut microbiota and its activity might be associated not only with the onset of inflammation...
They identified specific markers for mast cells in a mouse model and found that blocking histamine activity can decrease the severity of OA symptoms and the release of substances associated with OA [57]. Gut Microbiota and Adaptive Immunity Recent studies have specifically focused on the impact of...
In this co... X Li,Y Shimizu,I Kimura - 《Bioscience of Microbiota Food & Health》 被引量: 7发表: 2017年 ACOD1 deficiency offers protection in a mouse model of diet-induced obesity by maintaining a healthy gut microbiota Aconitate decarboxylase 1 (ACOD1) is the enzyme synthesizing ...
Metabolic syndrome (MS) comprises central obesity, increased plasma glucose levels, hyperlipidemia and hypertension, and its incidence is increasing due to changes in lifestyle and dietary structure in recent years. MS has been proven to be associated wi
Research about the role of gut microbiome in colorectal cancer (CRC) is a newly emerging field of study. Gut microbiota modulation, with the aim to reverse established microbial dysbiosis, is a novel strategy for prevention and treatment of CRC. Different strategies including probiotics, prebiotics,...
Effects of resveratrol on gut microbiota and fat storage in a mouse model with high-fat-induced obesity. Qiao Y, Sun J, Xia S, Tang X, Shi Y, Le G. 2014. Effects of resveratrol on gut microbiota and fat storage in a mouse model with high-fat-induced obesity. Food Funct 5:1241-...
Gut microbiotaThe direct treatment of obesity and its associated metabolic disorders using Bacillus natto was investigated in a high-fat diet (HFD) obesity mouse model. After 8 weeks of treatment, B. natto significantly reduces the body, epididymal fat, perirenal fat, liver, and spleen weight ...
Converging studies have shown that the gut microbiota composition and activity possibly contribute to shape host metabolism. A new study deeply analysed metabolic parameters in humans with obesity after short-term antibiotic exposure; the conclusion calls into doubt some direct and simple associations foun...
In the present study, we characterized the distinctive signatures of the gut microbiota (GM) from overweight/obese patients (OB), and normal-weight controls (NW), both of Sardinian origin. Fecal bacterial composition of 46 OB patients (BMI = 36.6