However, whether high dosage of CPFX has side effects on gut barrier integrity is still unclear. Our results indicated that the High CPFX treatment (1mg/ml) caused weight loss, nervousness, anorexia, and increased apoptosis cells in gut, but less influence was observed in the Low CPFX group...
Kissileff HR, Pi-Sunyer FX, Thornton J, Smith GP . C-terminal octapeptide of cholecystokinin decreases food intake in man. Am J Clin Nutr 1981; 34: 154–160. Article CAS PubMed Google Scholar West DB, Fey D, Woods SC . Cholecystokinin persistently suppresses meal size but not food inta...
reducing LPS and proinflammatory cytokines, and increasing SCFA production. Omega 3 FAs may exert beneficial effects on the gut microbiota by reducing the proliferation ofEnterobacteriaceae, increasing the proliferation ofBifidobacterium, and subsequently inhibiting the inflammatory ...
2018), integrative studies on diet shaped microbiota-host interactions have the potential to offer us novel insight on CVD mechanisms. From the microbiota side, there is big room to study molecular genetics mechanisms by which how the physiology and pathology relevant microbiota ...
25. Cheng XS, Shi FX, Zhao KP, Lin W, Li XY, Zhang J, et al. Nmnat2 attenuates amyloidogenesis and up-regulates ADAM10 in AMPK activity-dependent manner. Aging (Albany NY). 2021;13(20):23620–36. 26. Ali YO, Allen HM, Yu L, Li-Kroeger D, Bakhshizadehmahmoudi D, Hatcher ...
Bile acids were recognized as signaling molecules that have effects in multiple tissues due to the discovery of two bile acid receptors, FXR and GPBAR1. Within the gut, GPBAR1 is expressed on enteroendocrine cells and stimulate the release of multiple gut hormones [4] such as GLP1, GLP2, ...
The adipoinsular axis: effects of leptin on pancreatic 60 Kissileff HR, Pi-Sunyer FX, Thornton J, Smith GP. C-terminal octapeptide of beta-cells. Am J Physiol Endocrinol Metab 2000; 278: E1 - E14. cholecystokinin decreases food intake in man. Am J Clin Nutr 1981; 34: 154 - 160. 33...
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(https://lifescience.roche.com/en_gb/brands/universal-probe-library.html). Assay designs are provided in Supplementary Table2. PCR plates were loaded using the Biomek FX liquid handling robot (Beckman Coulter) and reactions [10 ng cDNA, 0.1 μM UPL probe, 0.2 μM forward primer,...
Smith PL, Myers JT, Rogers CE, Zhou L, Petryniak B, Becker DJ, Homeister JW, Lowe JB 2002 Conditional control of selectin ligand expression and global fucosy- lation events in mice with a targeted mutation at the FX locus. J Cell Biol 158:801–815 96. Newburg DS, Frankel DL, Fill...