The biology of the gut-brain axis is central to the efficacy of glucagon-like peptide-1 (GLP-1) - based therapies, which are now leading treatments for type 2 diabetes (T2DM) and obesity. This success, and research to suggest a much broader role for gut-brain circuits in physiology and...
1 The role of gut microbiota in the gut-brain axis: current challenges and perspectives 肠道微生物群在肠脑轴中的作用:当前的挑战和前景 Xiao Chen , Roshan D’Souza , Seong-Tshool Hong Bohrium | 2013-05-18 | Protein and Cell 大脑和胃肠道(GI)密切相连,形成一个双向的神经体液通信系统。肠道和...
In 2016, key studies have increased our understanding of the part played by the brain–gut–microbiota axis in disorders as diverse as depression, obesity and autism spectrum disorder. The data indicate that alterations in gut-microbial composition can substantially affect central physiology, and that...
They are considered to result from the interaction of altered gut physiology and psychological factors via the gut-brain axis, where brain and gut symptoms are reciprocally influencing each others expression. Intestinal microbiota, as a part of the gut-brain axis, plays a central role in FGIDs. ...
gut microbiota; immune modulation; neuroinflammation; neurodegeneration; mast cells; probiotics; gut–brain axis; microbial products; Toll-like receptors1. Introduction The gastrointestinal (GI) tract is an organ system responsible for transporting, absorbing, digesting, and excreting food and waste, as ...
In a striking display of trans-kingdom symbiosis, gut bacteria cooperate with their animal hosts to regulate the development and function of the immune, metabolic and nervous systems through dynamic bidirectional communication along the ‘gut–brain axis’. These processes may affect human health, as...
THE MICROBIOTA-GUT-BRAIN AXIS - A COMPLEX SYSTEM CROSS-TALK Physiology / FiziologiaIEκANU, MARA IOANAZAHIU, CARMEN-DENISE-MIHAELAGEORGESCU, IOANA ANTOANETAZGREAN, LEONZGREAN, ANA-MARIA
Here, we investigate the role of the gut-brain axis in gastric dysfunction during... P Bercik,EF Verdú,JA Foster,... - 《American Journal of Physiology Regulatory Integrative & Comparative Physiology》 被引量: 215发表: 2009年 Gut-brain axis: regulation of glucose metabolism. Top of pageGut...
The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner. Mol Psychiatry. 2013;18(6):666–73 doi:10.1038/mp.2012.77. CrossRef Collins SM, Surette M, Bercik P. The interplay between the intestinal microbiota and the brain. Nat ...
M. Gut:liver:brain axis: the microbial challenge in the hepatic encephalopathy. Food Funct. 9, 1373–1388 (2018). Article CAS PubMed Google Scholar Patel, V. C. et al. Rifaximin-α reduces gut-derived inflammation and mucin degradation in cirrhosis and encephalopathy: RIFSYS randomised ...