Microbiome-gut-brain axisCohortBackground:Microbiome-gut-brain axis may be involved in the progression of age-related cognitive impairment and relevant brain structure changes,but evidence from large human cohorts is lacking.This study was aimed to investigate the associations of gut microbiome with ...
Buqi-Huoxue-Tongnao decoction drives gut microbiota-derived indole lactic acid to attenuate ischemic stroke via the gut-brain axis Yarui Liu Peng Zhao Jie Zhao Chinese Medicine (2024) Dietary fibre directs microbial tryptophan metabolism via metabolic interactions in the gut microbiota Anurag K...
The concept of a gut–brain axis, with the microbiota influencing bidirectional gut-brain pathways, has become established in recent years41,42. There are thought to be three main pathways for this bidirectional communication: neural, immune, and endocrine41,43,44. Indeed, there is a growing bo...
Gut-Liver Axis Communication by Microbiota-Derived Lactate Programs Kupffer Cells to Clear Pathogens from the Bloodstream The ability of commensal microbes residing in the gut lumen to regulate immune cell activity downstream in the liver implies a mechanism of long-distance communication between these ...
We used two human cohorts in the present study: GNHS, as a discovery cohort37and GGMP, as a validation cohort38. We integrated multi-omics data from the GNHS to investigate whether the gut microbiota-bile acid axis contributed to the positive association between chronic insomnia and CMD, and...
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Microbiota–neuroepithelial signalling across the gut–brain axis Takahiro E. Ohara Elaine Y. Hsiao Nature Reviews Microbiology(2025) Organic food consumption is positively associated with cognitive function among middle-aged and older adults: cross-sectional and longitudinal analyses ...
In addition to treating GI disorders, neuromodulation has the potential to treat neurodegenerative diseases such as Alzheimer’s and Parkinson’s6,7, as it has been shown that the central and peripheral nervous systems are interrelated through the microbiota-gut-brain axis8,9,10. Fig. 1: The ...
We used two human cohorts in the present study: GNHS, as a discovery cohort37and GGMP, as a validation cohort38. We integrated multi-omics data from the GNHS to investigate whether the gut microbiota-bile acid axis contributed to the positive association between chronic insomnia and CMD, and...
Microbiota metabolites and especially SCFAs (Short-Chain Fatty Acids) connect different areas of the organism, through the mediation of the immune and hormone system, such as the so called gut-brain axis [6,10,11] suggesting that the crosstalk between the organism and its microbial residents is...