The GS-X pump is suggested to contribute to vesicle-mediated excretion of GSH-drug conjugates from cells. In addition, both HL-60 and HL-60/R-CP cells underwent cell differentiation in response to 12-O-tetradecanoylphorbol-13-acetate, retinoic acid, and dimethyl sulfoxide, resulting in ...
Differences in substrate specificity among glutathione conjugates (GS-X) pump family members: comparison between multidrug resistance-associated protein and a novel transporter expressed on a cisplatin-resistant cell line (KCP-4). Jpn. J. Cancer Res., 90: 439 - 447, 1999....
Glutathione-associated Biological Function of MRP/GS-X Pump and Its Gene Expression. 来自 t2r2.star.titech.ac.jp 喜欢 0 阅读量: 14 作者:T Ishikawa,MT Kuo,K Furuta,M Suzuki 摘要: , Glutathione-associated Biological Function of MRP/GS-X Pump and Its Gene Expression....
The discovery of the Multidrug Resistance-associated Protein (MRP or MRP1) as a GS-X pump able to transport both anionic drug conjugates and unmodified ant... P Borst,M Kool,R Evers - 《Seminars in Cancer Biology》 被引量: 209发表: 1997年 Resistance to cisplatin. Resistance to -diammine...
Expression of the MRP1 gene encoding the GS-X pump and of the γ-GCSh gene encoding the heavy (catalytic) subunit of the γ-glutamylcysteine synthetase is frequently elevated in many drug-resistant cell lines and can be co-induced by many cytotoxic agents. However, mechanisms that regulate ...
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The filter nozzle forms a nozzle channel between the filter nozzle and the pump housing. The nozzle channel is in connection with an annular recess, which is formed in the filter outlet part. The annular recess, will the hydraulic fluid from a governor valve to the distribution in an inlet ...
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