The GS-X pump is suggested to contribute to vesicle-mediated excretion of GSH-drug conjugates from cells. In addition, both HL-60 and HL-60/R-CP cells underwent cell differentiation in response to 12-O-tetradecanoylphorbol-13-acetate, retinoic acid, and dimethyl sulfoxide, resulting in ...
GS-X pumpMRPSubstrate specificityThe substrate specificity of primary active transporters expressed on two kinds of human epidermoid KB-3-1 derived cell lines, C-A500 and KCP-4, was examined; the former expresses multi-drug resistance-associated protein (MRP1), whereas the latter is resistant to...
Expression of the MRP1 gene encoding the GS-X pump and of the γ-GCSh gene encoding the heavy (catalytic) subunit of the γ-glutamylcysteine synthetase is frequently elevated in many drug-resistant cell lines and can be co-induced by many cytotoxic agents. However, mechanisms that regulate ...
The discovery of the Multidrug Resistance-associated Protein (MRP or MRP1) as a GS-X pump able to transport both anionic drug conjugates and unmodified ant... P Borst,M Kool,R Evers - 《Seminars in Cancer Biology》 被引量: 209发表: 1997年 Resistance to cisplatin. Resistance to -diammine...
Glutathione-associated Biological Function of MRP/GS-X Pump and Its Gene Expression. 来自 t2r2.star.titech.ac.jp 喜欢 0 阅读量: 14 作者:T Ishikawa,MT Kuo,K Furuta,M Suzuki 摘要: , Glutathione-associated Biological Function of MRP/GS-X Pump and Its Gene Expression....
Pump Body: Cast iron Impeller: Stainless steel or cast iron Motor Shaft: stainless steel Mechanical Seal: Ceramic- graphite Electric Motor: Single- phase 230V- 50Hz with condenser and thermal overload protector built into the copper winding. Three- phase 380/ 400V- 50Hz. ...
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Posttranscriptional regulation of MRP/GS-X pump and gamma-glutamylcysteine synthetase expression by 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroet... Treatment of human glioma A172 cells with 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethy-3-nitrosourea (ACNU) for 2...
➢ GS series is in the G series development to the special for the food industry design quick cleaning single screw pump, the difference is that the special pump, "S" represents the meaning is quick cleaning, every part of the any small parts can be cleaned very clean. ➢ GS series ...