ChildrenGrowthHormoneDeficiencyShortStatureBackground: Growth hormone deficiency is an important and treatable cause for short stature in early diagnosed cases. This study was conducted to determine the frequency of growth hormone deficiency in children with short stature referred. Methods: In a cross ...
The growth hormone (GH)–insulin-like growth factor (IGF) axis consists of central neuro-anatomical, regulatory and genetic systems, and the peripheral intracellular GH signalling pathway The introduction of recombinant human GH (rhGH) in 1985 ended the phase of pituitary-derived human growth hormone...
Growth hormone deficiency can occur at any age. Growth hormone is necessary for normal growth and development in children. In adults, growth hormone is needed to maintain the proper amounts of body fat, muscle, and bone. In adults, low or absent growth hormone can also cause emotional symptom...
Objectives Benign Hereditary Chorea (BHC) (MIM 118700) is a rare childhood-onset movements disorder characterized by non-progressive chorea. It is usually caused by variants in the thyroid transcription factor 1 (TITF-1/NKX2-1) gene and it is associated
Growth hormone treatment in children is not associated with an increase in the incidence of cancer: experience from KIGS (Pfizer In- ternational Growth ... P Wilton,AF Mattsson,F Darendeliler - 《Journal of Pediatrics》 被引量: 0发表: 2010年 The oncogenic potential of growth hormone. Growth...
In any indication the response to GH seems correlated to the dose and the duration of treatment. GH treatment is generally safe with no major adverse effects being recorded in any condition. 展开 关键词: Children growth hormone puberty short stature ...
CHARACTER-SPECTRUM DISORDERDSTTRH-TSH TESTPediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from molecular biology to epidemiology. Use of model organisms and in vitro techniques relevant to ...
improve-mentsinclinicalstatus.Inourexperience,improvedgrowthandweightstatushavebeenassociatedwithfewerhospitalizations,fewerantibioticcourses,andimprovedpulmonaryfunction.Alargemulticentertrialiscurrentlyunderwaytoassesstheeffectoflong-termtherapywithGHonthequalityoflifeandpulmonarystatus.KEYWORDSgrowthhormonetreatment,children,...
Thyroid hormone levels in children with Prader-Willi syndrome before and during growth hormone treatment. Clin Endocrinol (Oxf) 2007;67:449-56.Festen DA, Visser TJ, Otten BJ, et al. Thyroid hormone levels in children with Prader-Willi syndrome before and during growth hormone treatment. Clin ...
Response to Growth Hormone Therapy in Children with Noonan Syndrome: Correlation with or without PTPN11 Gene Mutation (vol 77, pg 388, 2012) Noonan syndrome (NS; OMIM 163950) is an autosomal dominant disorder with variable clinical expression and genetic heterogeneity. Clinical manifestations in......