The B cell antigen receptor (BCR) employs enzymatically inactive adaptor proteins to facilitate activation of intracellular signaling pathways. In animal model systems, adaptor proteins of the growth factor receptor-bound 2 (Grb2) family have been shown to serve critical functions in lymphocytes. Howev...
In contrast, compared to the HGAL knockdown, knockdown of Grb2 significantly increased lymphoma cell chemotaxis in response to SDF-1. Concomitandoi:10.1182/blood.V120.21.681.681Xiaoyu JiangXiaoqing LuIzidore S Lossos
In some cases may progress to a B-cell malignancy or myeloma. gamocyte Rarely used term for a phase of the life cycle of protozoa such as Plasmodium that develops from the trophozoite and later gives rise to gametes. gamone A pheromone released by a gamete or hypha and that is ...
CELL-MIGRATIONERK ACTIVATIONMAP KINASESSH3 DOMAINSRASThe adaptor protein growth factor receptor-bound protein 2 (Grb2) is ubiquitously expressed in eukaryotic cells and involved in a multitude of intracellular protein interactions. Grb2 plays a pivotal role in tyrosine kinase-mediated signal transduction...
Involvement of GRB2 in Ras-signaling pathway has been reported, recent finding show that GRB2 may also play a complex role in T and B-cell antigen receptor signaling. Properties Storage Instructions All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of ...
参考文献 Su J , Wu G , Ye Y , et al. NSUN2-mediated RNA 5-methylcytosine promotes esophageal squamous cell carcinoma progression via LIN28B-dependent GRB2 mRNA stabilization.[J]. Nature Publishing Group, 2021(39).
Involvement of GRB2 in Ras-signaling pathway has been reported, recent finding show that GRB2 may also play a complex role in T and B-cell antigen receptor signaling. 实验方案 Product Specific Protocols IF protocol for CL Plus 488 GRB2 antibody CL488-66880 Download protocol Standard Protocols ...
[17]GuoL, LiB, MiaoM, et al. MicroRNA-663b targets GAB2 to restrict cell proliferation and invasion in hepatocellular carcinoma[J]. Mol Med Rep, 2019, 19(4): 2913-2920. DOI: 10.3892/mmr.2019.9934.
Involvement of GRB2 in Ras-signaling pathway has been reported, recent finding show that GRB2 may also play a complex role in T and B-cell antigen receptor signaling. 实验方案 Product Specific Protocols IF protocol for CL594 GRB2 antibody CL594-66880 Download protocol Standard Protocols Click ...
N-SH3 domain of Grb2 was involved in the protein vesicular localization including amyloid-β protein precursor (AβPP). Involvement of GRB2 in Ras-signaling pathway has been reported, recent finding show that GRB2 may also play a complex role in T and B-cell antigen receptor signaling....