Decreased expression of PROX1 was found in hepatocellular carcinomas, sporadic breast cancer and carcinomas of the biliary system (Shimoda et al, 2006; Laerm et al, 2007; Versmold et al, 2007). In contrast, PROX1 was overexpressed in colorectal cancer and found to have a role in promoting...
The medical chart review abstracted information on ages, diagnosis, and pathological data such as tumour stages and grade in addition to status of lymph nodes and distant organ or tissue metastases. Ectopic cancer metastases were mainly diagnosed from CT scan, MRI, or PET-CT, demonstrating ...
Genomic predisposition to EOC shows that HGSC is chromosomally highly unstable and harbors tumor protein 53 (TP53) mutations and mutations of breast cancer 1 (BRCA1) and breast cancer 2 (BRCA2) [2]. Although expression of the BRCA gene is a predictive biomarker for outcome on poly ADP-ribose...
METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N(6)-methyladenosine modification of PD-L1 mRNA in breast cancer. Mol Cancer. 2022;21(1):60. Article PubMed PubMed Central CAS Google Scholar Wang W, He Y, Zhai LL, Chen LJ, Yao LC, Wu L, Tang ZG, Ning JZ....
In breast and endometrial cancers, the use of panels of estrogen-induced genes has improved prognostic capability over the use of ER alone. For both breast and endometrial cancer, over-expression of estrogen-induced genes is associated with better prognosis. We hypothesized that estrogen-induced ...
In breast cancer, PTEN loss is more prevalent in asso- ciation with BRCA1 germ-line mutations, and tumour analysis at the single-cell level has shown that it is the most common initiating event in BRCA1-associated breast tumours [7,8]. Owing to our small sample size, our results suggest...
It is the second most common cancer after breast cancer. The incidence of cervical carcinoma in Thailand is 24.5:100,000 (age-standardized incidence rate) and 10,000 newly detected cases, each year [1]. Many screening strategies were established with the aim to early detect preinvasive lesion...
aNotably FOS, which is one of the most differentially expressed genes between the two time points was implicated in both hypoxia and other breast cancer gene signatures 著名FOS,是其中一个最有差别地表达的基因在二次点之间在低氧症和其他乳腺癌基因署名被牵连了[translate] ...
These data will further characterize epigenomic phenomena that contribute to heterogeneity in the biology and behavior of ovarian cancer and inform future therapeutic decision making. Materials and Methods Tissue procurement and processing We carried out a retrospective chart review to identify patients with...
Recent evidence described that lower levels of PD1 expression could increase the survival rate in breast cancer patients41. In addition to this, we have also identified several transcriptions and translation factors such as elongation factor gamma, eukaryotic translation initiation factor 3 subunit, ...