Studies have also shown that when embryos are damaged during development, there is increased activity in terms of metabolism, stress, and other aspects, leading them to produce more reactive oxygen species and ATP compared with normal embryos. Therefore, metabolic disorders and imbalances in vivo ...
2021;11(8):1896–912. Article CAS PubMed PubMed Central Google Scholar Maiorano BA, Maiorano MFP, Cormio G, Maglione A, Lorusso D, Maiello E. How immunotherapy modified the therapeutic scenario of endometrial cancer: a systematic review. Front Oncol. 2022;12: 844801. Article CAS Pub...
Variable combinations of additional mutations also contribute to intertumoral heterogeneity, including mutations activating the receptor tyrosine kinase–RAS–PI3-kinase pathway, alterations inactivating tumor suppressors TP53 or CDKN2A, mutations in epigenetic regulators such as ATRX, and others5,6,9,10,11...
Topoisomerase IIα decatenates kDNA which consists of highly catenated networks of circular DNA in an ATP-dependent reaction to yield individual minicircles of DNA. In brief, for topoisomerase IIa–mediated kDNA decatenation assay, the 20-μl reaction mixture contains the following components: 50...
We selected small (pT1c, 11–20 mm) tumors to keep potential sampling error as low as possible, to capture metastasis-responsible cell population. Although this approach is sufficient for this purpose, we also wished to study whether low grade metastasis-associated proteins differ from those ...
Active efflux of molecules is mediated by ATP-binding cassette (ABC) proteins, which are highly expressed within the CNS and limit the permeability of the BBB to toxins and therapeutic molecules [37]. The main ABC proteins include Breast Cancer Resistance Protein (BRCP, ABCG2) and P-glycoprot...
ABCG2: ATP-binding cassette subfamily B member 2; ADC, apparent diffusion coefficient; aDMG, adult diffuse midline glioma; advMRI, advanced MRI; AI, artificial intelligence; 5-ALA, 5-aminolevulinic acid; ANN, artificial neural network; APT, amide proton transfer; APTw, amide proton transfer ...
Here, all of the five samples exhibit the similar characteristic diffraction peaks of the ATP, and those of quartz, muscovite, and other impurity minerals are not obvious. After the hydrothermal reaction, the intensity of the characteristic diffraction peaks of attapulgite slowly weakens with the ...