产品名称: Recombinant Human gp100重组蛋白 别名: 95 kDa melanocyte specific secreted glycoprotein; 95 kDa melanocyte-specific secreted glycoprotein; D12S53E; gp100; M-beta; ME20; ME20 M/ME20 S; ME20-M
Taken together, these data show a high frequency of Pmell7/gp100-specific T cells in autologous antitumor CTL clones derived from peripheral blood of a melanoma patient. 展开 关键词: CTL immunotherapy melanoma DOI: 10.1111/1523-1747.ep12298177 ...
The silver locus product (Silv/gp100/Pmel17) as a new tool for the analysis of melanosome transfer in human melanocyte–keratinocyte co‐culture Melanosomes are melanocyte-specific lysosome-related organelles that are transferred to keratinocytes of the epidermis and anagen hair bulb. Transferred me...
//www.bjcancer.com Keywords: tyrosinase; gp 100/pmel17; melanoma; helper T cells; ELISPOT; vaccine The recent understanding of the molecular basis of T cell recogni- tion of human tumours has allowed for the development of vaccine trials targeting the induction of antigen-specific, tumour-...
Expression of Gp100 is most useful clinically as a diagnostic marker of melanoma. Its role as a therapeutic target is currently under investigation. The peptide gp100:209–217 (210 M) in Montanide ISA-51 (incomplete Freund’s adjuvant) in combination wit
This allele has thus been extensively used as a specific dominant-negative mutant.2, 56, 57 Adenoviral infection efficiency approached 100% in these cells, based on GFP signal (data not shown) and was shown to produce strong expression of wild-type or mutant MITF by Western blot (data not ...
13, no. 1, pp. S48-S51, 1999.Nawrath M,Pavlovic J,Dummer R,et al.Reduced melanoma tumor formation in mice immunized with DNA expression the melanoma-specific antigen gp100/pmel. Leukemia . 1999Heinrich J,Pavlovic J,Dummet R,etc.Reduced melanoma tumor formation in mice immunized with DNA ...
Melanoma-specific immunogen comprising epitopes homologous with pMel17; HLA-A2-restricted epitope, melanoma tumor-associated antigen pMel-17 and/or tyrosin... Current approaches to adoptive T cell therapy for cancer and chronic viral infection are limited by the difficulty of obtaining sufficient number...
To date, there have been no reports that address this issue regarding melanosome-specific proteins. The putative function(s) of iPmel17, which is the major form of Pmel17 seen in pigmented cells, is a matter of conjecture and controversy at this point (16, 17). The rapid processing of ...
(1999). Reduced melanoma tumor formation in mice immunized with DNA expressing the melanoma-specific antigen gp100/pmel17. Leukemia 13 , S48–51.Nawrath M,Pavlovic J,Dummer R,et al.Reduced melanoma tumor formation in mice immunized with DNA expression the melanoma-specific antigen gp100...