Uric acid crystals can form when the blood level of uric acid is high. Uric acid is a breakdown product of purines (found naturally in the body and certain foods). Naturally, uric acid is excreted into the urine. However, abnormalities can occur, and the body produces too much, or the...
Medicationscan also help preventgoutattacks if you have them often. These drugs decrease the production of uric acid or increase the amount of uric acid you get rid of in urine. These medicines includeallopurinol(Aloprim,Lopurin,Zyloprim),colchicine (Colcrys,Gloperba,Mitigare),pegloticase(Krystexxa...
but that’s not the whole story. Once a flare ends gout doesn’t go away. If you’re uric acid level stays too high despite treatment crystals keep building up and your gout may become out of control. Doctors refer to this as uncontrolled gout. Without proper treatment you’re at risk...
are normally steadily excreted into theurine. Gout accounts for at least 5 percent of all cases ofarthritis. However, it is uncommon in women; the male-female ratio is 20:1.Pseudogout(chondrocalcinosis) is a similar condition caused by deposits of calcium pyrophospate crystals in the joints....
1.痛风作为"慢性病"(chronic condition)的"急性发作"称为gout flare 2.上文中提到的acute inflammatory arthritis指的就是这种"急性炎症性关节炎"的表现 3.Uric acid意为"尿酸",原形是"尿液"urine 4.Hyperuricemia意为"高尿酸血症" 5.Crystal意为"水晶",urate crystal意为"尿酸晶体" ...
It passes through the kidneys and out of the body in urine. But uric acid can build up in the blood when:The body increases the amount of uric acid it makes. The kidneys do not get rid of enough uric acid. A person eats too many foods high in purines....
Uric acid is a chemical that’s carried through the blood. Most is removed by the kidneys through urine. Even with oral medication, people with out-of-control gout can have a hard time getting rid of uric acid. Over time, uric acid can build up and form crystals that settle in the jo...
your urine. But now and again both your frame produces an excessive amount of uric acid or your kidneys excrete too little uric acid. When this happens, uric acid can construct up, forming sharp, needle-like urate crystals in a joint or surroundingtissuethat reason ache, infection and ...
causing stiffness and deformity. The aim of treatment is to minimize the formation of uric acid crystals. A high liquid intake that increases daily urine output is usually recommended. An acute attack of gout is usually treated with nonsteroidal anti-inflammatory drugs, such as indomethecine or...
Lopez-Reyes A, Medina-Luna D, Santamaria-Olmedo M, Martinez-Flores K, Zamudio-Cuevas Y, Fernandez-Torres J, et al. Soluble inflammatory mediators of synoviocytes stimulated by monosodium urate crystals induce the production of oxidative stress, pain, and inflammation mediators in chondrocytes: Secr...