As all of the APIs for which tosylate salts are used are administered in high doses and tosylate represents a counterion with a high molar mass of 172g/mol, it becomes obvious that there must be special benefits such as e.g. improved dissolution rate from the usage of tosylate-salts in ...
commonly referred to as aflare.This flare can last anywhere from days to weeks. Once the receptors have become desensitized, GnRH is inhibited, and the antiandrogenic effects of the drug are seen. The flare can result in a temporary worsening of the clinical condition before benefits are seen...