α-L-Fucosidases (EC 3.2.1.51), the only members of glycoside hydrolase family 29, are involved in many biological processes like inflammation, growth regulation, receptor interactions, and antigenicity. Their
Yang J, Zhang X, Yoon J, Rao K, Grate JH, Baidyaroy D, Elgart DD. February 2013. Gh61 glycoside hydrolase protein variants and cofactors that enhance gh61 activity. US patent 20,130,052,698.Yang J, Zhang X, Yoon J, Rao K, Grate JH, Baidyaroy D, Elgart DD. February 2013. Gh...
The name assigned to the new GH family is GH148. Based on amino acid sequence and in consequence also structural similarity, glycoside hydrolase (GH) enzymes are grouped into GH families, as comprehensively documented in the carbohydrate-active enzymes (CAZy) data- base (http://www.cazy.org/...
This article contains supplemental Figs. S1 and S2. 1 Both authors contributed equally to this work. 3 The abbreviations used are: GH18 glycoside hydrolase family 18 pNP 4-nitrophenolate ITC isothermal titration calorimetry MU methylumbelliferyl PDB Protein Data Bank. ...
et al. Discovery of novel carbohydrate-active enzymes through the rational exploration of the protein sequences space. Proc. Natl Acad. Sci. USA 116, 6063–6068 (2019). Article CAS PubMed PubMed Central Google Scholar Ishida, T. et al. Crystal structure of glycoside hydrolase family 55 β...
Protein Structure, TertiarySubstrate SpecificityHydrolysisGenome, BacterialAmino Acid MotifsMembers of glycoside hydrolase family 1 (GH1) cleave glycosidic linkages with a variety of physiological roles. Here we report a unique GH1 member encoded in the genome of Bifidobacterium adolescentis ATCC 15703. ...
This novel BmaN1 α-amylase is part of a group of α-amylases that all have this atypical catalytic triad, consisting of aspartic acid, glutamic acid and histidine. Phylogenetic analysis showed that this group of α-amylases comprises a new subfamily of the glycoside hydrolase family 13....
Yanhong Liu1, Jigang Yu1, Fudong Li2, Hui Peng1, Xuecheng Zhang1,Yazhong Xiao1 & Chao He1 Subfamily 37 of the glycoside hydrolase family GH13 was recently established on the basis of the discovery of a novel α-amylase, designated AmyP, from a marine metagenomic library...
a Structure of glycoside hydrolase protein CpEng1. b Amino acid sequence of Eng1 for Cryphonectria parasitica and other species (red box indicates the active structural domain feature). c Phylogenetic analysis of Eng1 Full size image To reveal the function of CpEng1 during the infection process,...
Gerwig1, Stéphane Duboux2, Christina Vafiadi2, Tjaard Pijning3 & Lubbert Dijkhuizen1 Lactic acid bacteria possess a diversity of glucansucrase (GS) enzymes that belong to glycoside hydrolase family 70 (GH70) and convert sucrose into α-glucan polysaccharides with (α1 → 2...