Hayashi T, Maclachlan G. Glycolipids and glycoproteins formed from UDP- galactose by pea membranes. Phytochemistry Pergamon. 1984 Jan 1;23(3):487-92.Hayashi T, Maclachlan G (1984) Glycolipids and glycoproteins formed from UDP-galactose by pea membranes. Phytochemistry 23: 487-492...
However, in cells, galectins bind glycans on glycoproteins and glycolipids in the context of other cellular components, such as at the cell surface. Because of difficulties in characterizing natural cellular environments, we currently lack a detailed understanding of galectin-binding specificities in ...
Typically, sialic acid is found as a component of the oligosaccharide chains of mucins, glycoproteins, and glycolipids occupying terminal, nonreducing positions of N- or O-glycans. Sialic acid levels in serum are associated with liver diseases46, rheumatic diseases47, and type-2 diabetes48. In ...
Glycoproteins are complex macromolecules composed of a polypeptide backbone to which one or more carbohydrate units are attached. Based on the linkage between the peptide and sugar, one can classify several types of glycoproteins (Spiro, 1970). The linkage betweenN-acetylglucosamine and asparagine throu...
Myelin is formed as an extension and modification of the surface membrane of the oligodendrocyte in the central nervous system (CNS) and the Schwann cell in the peripheral nervous system (PNS). The extended plasma membranes are wrapped around the axons i
Moreover, ST3Gal VI prefers oligosaccharides containing the terminal Galβ1,4GlcNAc structure much more than those containing the Galβ1,3GlcNAc structure, suggesting it is involved in the formation of the sialyl-Lex determinant on glycoproteins and glycolipids. The expression of the gene among ...
sLea from cancer patient serum was found on mucins (8), and it is reported on both mucins (9) and glycolipids (10) in adenocarcinoma cell lines. Five β3Gal-T cDNAs are presently available. β3Gal-T1, cloned first from melanoma cells (11) and then from colon carcinoma cells (12), ...
Glycans are usually found on the cells in the form of glycoproteins or glycolipids, where they are covalently attached to either proteins or lipids, respectively. Since the focus of this tutorial is on the structural characterization of glycans associated with proteins, only protein glycosylation is ...
The glycolipids containing Galα1–4Gal are known as targets on host cells for infections of some pathogenic microbes,e.g. uropathogenic Escherichia coli (9, 10),Pseudomonas aeruginosa (PA-I lectin) (11), andStreptococcus suis (12, 13, 14). Bacterial enterotoxins,e.g. from E. coli (...
This chapter focuses on glycoproteins, which are a wide range of compounds of diverse structure and function, and are components of cell membranes, intercellular matrices, and extracellular fluids, such as plasma. They occur in soluble and membrane-bound forms. The proportion of carbohydrates varies...