Gaede G.: Glycogen phosphorylase in the fat body of the cockroach species, Periplaneta americana and Nauphoeta cinerea: Isolation, partial characterization of 3 forms and activation by hypertrehalosaemic hormone. Z. Naturforsch. Sect. C 46: 149–162 (1991) Google Scholar Gamblin S. J. et al...
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Under physiological conditions, glycolysis serves as the primary mode of energy production in ECs, exhibiting a higher proportion compared to other cells in the body. Similar to many cancer cells, up to 85% of ATP is produced by glycolysis in ECs. This phenomenon can be attributed to two poss...
During activation, T cells undergo metabolic reprogramming, which imprints distinct functional fates. We determined that on PD-1 ligation, activated T cells are unable to engage in glycolysis or amino acid metabolism but have an increased rate of fatty a
Download: Download full-size image Figure 3. PD-1 pathway blockade by anti-PD-1 blocking mAb restored the basal glycolytic rate and maximum glycolytic capacity in activated CD4+ T cells inhibited by MSCs. The ECAR for each group was measured in real time at the basal condition and after the...
Download: Download high-res image (2MB) Download: Download full-size image Fig. 1. Ad-apoptin inhibits the proliferation of lung cancer cells by inducting apoptosis. To test whether Ad-mock and Ad-apoptin inhibited the proliferation of lung cancer cells by inducing apoptosis, we detected the ap...
The forming step is preferably spraying-drying, extruding, granulating and the like. The form and grain size of the additive particles are uniform and therefore its disintegration and dissolution velocity also uniform. Therefore, the effects of the additive on the blood, namely its capacity to prev...
Hexokinase-2 (HK2) is a key enzyme of the first step in glycolysis [22]. Here, we measured the glucose consumption, lactate production, and HK2 enzyme activity to evaluate the glycolysis process in lung cancer cells. The levels of glucose (ab65333; Abcam, Shanghai, China) and lactate (ab...
After the reaction, the catalyst can be quickly separated by filtration, so it can be easily reused without significant loss of reactivity at least five times. Therefore, the Pd-Cu/γ-Al2O3 catalyst may contribute to an economically and environmentally improved large-scale recycling of PET ...
(2,3). Consequently, metabolic programming of cancer cells is required to be flexible, which allows the cells to adapt to various environmental conditions. PKM2 is responsible for the final step of glycolysis and is key in this process (2,3). The preferential expression and allosteric enzymatic...