The network of xylose degradation allows to achieve carbon conservation also for the production of other target compounds, e.g. for derivatives of glycolaldehyde (as the C2 molecules glycolate or ethylene-glycol). A variant of the Weimberg pathway, the Dahms pathway, cleaves the intermediate 2-...
The biochemical strategy of human colon adenocarcinoma was studied by elucidating the enzymic programs of pyrimidine biosynthesis and degradation, glycolys... G Weber,MS Lui,E Takeda,... - 《Life Sciences》 被引量: 153发表: 1980年 Adrenal cells in tissue culture. VIII. Dissociation of the ster...
et al. The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1. Nat. Cell Biol. 11, 747–752 (2009). Article CAS Google Scholar Almeida, A., Bolaños, J. P. & Moncada, S. E3 ubiquitin ligase APC/C-Cdh1...
Adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) are key enzymes involved in intracellular degradation of triacylglycerols. It was the... Maria,Morak,Hannes,... - 《Molecular & Cellular Proteomics》 被引量: 36发表: 2012年 Increase in Glyceride Content of Brown Fat by Treatm...
For degradation assay, 20,000 cells were seeded in each well of a 24-well plate containing acid washed cover slips. Forty-eight hours after cell seeding, cells were fixed in 4% paraformaldehyde and stained with Alexa Fluor 555 Phalloidin (Life Technologies, Rockford, IL, USA) for 15 min ...
This chapter describes the regulation and mechanisms of enzymes, known as Glycosis, the stepwise degradation of glucose to pyruvate by way of fructose diphosphate found in almost all cells. The major features of the pathway are approximately the same through all life forms, suggesting the ...
Glycolysis is one of the two main pathways of carbohydrate degradation in most animal and plant tissues. The term glycolysis is generally considered to mean the anaerobic breakdown of reserve polysaccharide (eg. starch, glycogen), hexoses or hexose phosphates to pyruvate via the Embden-Meyehhof-Pab...
Department of Chemistry, Estahban Higher Education Center, 74519 44655, Estahban, Iran Roghayeh Heiran & Fatemeh Sedaghati Young Researchers and Elite Club, Shiraz Branch, Islamic Azad University, Shiraz, Iran Abolfazl Ghaderian International and Interuniversity Centre for Nanoscience and Nanotechnology...
8A). These genes are implicated in cell cycle regulation, RNA degradation, and ribosome biogenesis (Fig. 8B–C). Figure 8D enumerates the most significantly altered genes. Microarray findings were validated through real-time qPCR (Fig. 8E), providing concrete evidence supporting our microarray ...
Interestingly, recent studies demonstrated that the inhibition of glycolysis could induces DNA degradation and cell apoptosis through reducing ATP production12–14. Collectively, inhibition of the glycolytic pathway may be an appropriate target for inhibiting tumor growth and/or inducing apoptosis. However,...